Simple Summary Recently, our understanding of PFK-2 isozymes, particularly with regards
to their roles in cancer, has developed significantly. This review aims to compile the most …

Background Cancer cells favor the use of less efficient glycolysis rather than mitochondrial
oxidative phosphorylation to metabolize glucose, even in oxygen-rich conditions, a distinct …

Background Small cell lung cancer (SCLC) is the most aggressive subtype of lung cancer.
Although most patients are initially sensitive to first-line combination chemotherapy with …

Simple Summary The metabolism of carbohydrates and lipids is essential to meet the
diverse needs of cells. The autophagy cellular pathway is crucial for normal cellular function …

The functional effects of long noncoding RNAs (lncRNAs) in cancer have been widely
recognized. However, there is little research on SCLC-related lncRNAs. Here, long …

For a long time, pioneers in the field of cancer cell metabolism, such as Otto Warburg, have
focused on the idea that tumor cells maintain high glycolytic rates even with adequate …

Chicken lung is an important target organ of avian influenza virus (AIV) infection, and
different pathogenic virus strains lead to opposite prognosis. Using a single-cell RNA …

Rationale: The circadian clock coordinates cell proliferation and metabolism and impacts the
progression of some diseases, particularly cancer. Pharmacological modulation of the …

Upregulation of glycolysis, induction of epithelial–mesenchymal transition (EMT) and
macroautophagy (hereafter autophagy), are phenotypic changes that occur in tumor cells, in …

Background Kinases play critical role in clear-cell renal cell carcinoma (ccRCC). We aim to
exploit novel kinase that is both protumorigenic and drugable in ccRCC. Methods …