Circular RNAs in diabetes mellitus and its complications

W Fan, H Pang, Z Xie, G Huang, Z Zhou - Frontiers in Endocrinology, 2022 - frontiersin.org
Diabetes mellitus (DM) is an endocrine disorder characterized by a relative or absolute lack
of insulin due to the dysfunction or destruction of β-cells. DM is one of the fastest growing …

A comprehensive review on the phytochemistry, pharmacokinetics, and antidiabetic effect of Ginseng

Y Liu, H Zhang, X Dai, R Zhu, B Chen, B Xia, Z Ye… - Phytomedicine, 2021 - Elsevier
Abstract Background Radix Ginseng, one of the well-known medicinal herbs, has been used
in the management of diabetes and its complications for more than 1000 years. Purpose The …

A novel identified circular RNA, mmu_mmu_circRNA_0000309, involves in germacrone-mediated improvement of diabetic nephropathy through regulating ferroptosis …

J Jin, Y Wang, D Zheng, M Liang… - Antioxidants & redox …, 2022 - liebertpub.com
Aims: Diabetic nephropathy (DN) is characterized by microalbuminuria, mainly associated
with pathological and morphological alterations of podocyte. New drug targeting podocyte …

Circ_0114581 promotes osteogenic differentiation of BMSCs via the MiR-155-5p/HNRNPA3 axis

H Li, C Wang, J Yao, Y Jin, X Song, Q Meng, J Wu… - Life Sciences, 2023 - Elsevier
Osteoporosis (OP) is a common metabolic bone disease characterized by deterioration of
bone tissue structure, reduction of bone mass, and susceptibility to fracture. More and new …

Circ-ACTR2 aggravates the high glucose-induced cell dysfunction of human renal mesangial cells through mediating the miR-205-5p/HMGA2 axis in diabetic …

J Yun, J Ren, Y Liu, L Dai, L Song, X Ma, S Luo… - Diabetology & metabolic …, 2021 - Springer
Abstract Background Circular RNAs (circRNAs) have been considered as pivotal biomarkers
in Diabetic nephropathy (DN). CircRNA ARP2 actin-related protein 2 homolog (circ-ACTR2) …

[HTML][HTML] The role of circular RNA in Diabetic Nephropathy

C Tu, L Wang, L Wei, Z Jiang - International Journal of Medical …, 2022 - ncbi.nlm.nih.gov
Diabetic nephropathy (DKD) is the most common chronic microvascular complication of
diabetes. About 20%-40% of diabetics develop DKD, which eventually leads to chronic …

Epigenetic modification in diabetic kidney disease

Z Liu, J Liu, W Wang, X An, L Luo, D Yu… - Frontiers in …, 2023 - frontiersin.org
Diabetic kidney disease (DKD) is a common microangiopathy in diabetic patients and the
main cause of death in diabetic patients. The main manifestations of DKD are proteinuria …

Hsa_circ_0037128 aggravates high glucose-induced podocytes injury in diabetic nephropathy through mediating miR-31-5p/KLF9

R Fang, X Cao, Y Zhu, Q Chen - Autoimmunity, 2022 - Taylor & Francis
Background Circular RNA is a key regulator involved in the progression of many human
diseases including diabetic nephropathy (DN). However, the role and mechanism of …

Circ-FBXW12 aggravates the development of diabetic nephropathy by binding to miR-31-5p to induce LIN28B

A Sun, N Sun, X Liang, Z Hou - Diabetology & Metabolic Syndrome, 2021 - Springer
Background The involvement of circular RNAs (circRNAs) in diabetic nephropathy (DN) has
been gradually identified. In this study, we aimed to explore the functions of circRNA F …

Circular RNAs in diabetes and its complications: Current knowledge and future prospects

W Yin, Z Zhang, Z Xiao, X Li, S Luo, Z Zhou - Frontiers in genetics, 2022 - frontiersin.org
A novel class of non-coding RNA transcripts called circular RNAs (circRNAs) have been the
subject of significant recent studies. Accumulating evidence points that circRNAs play an …