The hepatic microcirculation: mechanistic contributions and therapeutic targets in liver injury and repair

B Vollmar, MD Menger - Physiological reviews, 2009 - journals.physiology.org
The complex functions of the liver in biosynthesis, metabolism, clearance, and host defense
are tightly dependent on an adequate microcirculation. To guarantee hepatic homeostasis …

Organ preservation: current concepts and new strategies for the next decade

EE Guibert, AY Petrenko, CL Balaban… - Transfusion Medicine …, 2011 - karger.com
Organ transplantation has developed over the past 50 years to reach the sophisticated and
integrated clinical service of today through several advances in science. One of the most …

Upconversion nanoprobes for the ratiometric luminescent sensing of nitric oxide

N Wang, X Yu, K Zhang, CA Mirkin… - Journal of the American …, 2017 - ACS Publications
By taking advantage of the optical properties of upconversion nanoparticles (UCNPs), we
have designed a luminescence ratiometric nanosensor for measuring nitric oxide (NO) in …

Hydrogen sulfide attenuates hepatic ischemia-reperfusion injury: role of antioxidant and antiapoptotic signaling

S Jha, JW Calvert, MR Duranski… - American Journal …, 2008 - journals.physiology.org
Hydrogen sulfide (H2S) is an endogenously produced gaseous signaling molecule with
diverse physiological activity. The potential protective effects of H2S have not been …

[HTML][HTML] Hepatic ischemia-reperfusion injury in liver transplant setting: mechanisms and protective strategies

S Rampes, D Ma - Journal of biomedical research, 2019 - ncbi.nlm.nih.gov
Hepatic ischemia-reperfusion injury is a major cause of liver transplant failure, and is of
increasing significance due to increased use of expanded criteria livers for transplantation …

Viability testing and transplantation of marginal livers (VITTAL) using normothermic machine perfusion: study protocol for an open-label, non-randomised, prospective …

RW Laing, H Mergental, C Yap, A Kirkham, M Whilku… - BMJ open, 2017 - bmjopen.bmj.com
Introduction The use of marginal or extended criteria donor livers is increasing. These
organs carry a greater risk of initial dysfunction and early failure, as well as inferior long-term …

Hydrogen sulfide and the liver

S Mani, W Cao, L Wu, R Wang - Nitric Oxide, 2014 - Elsevier
Hydrogen sulfide (H 2 S) is a gasotransmitter that regulates numerous physiological and
pathophysiological processes in our body. Enzymatic production of H 2 S is catalyzed by …

MG53 constitutes a primary determinant of cardiac ischemic preconditioning

CM Cao, Y Zhang, N Weisleder, C Ferrante, X Wang… - Circulation, 2010 - Am Heart Assoc
Background—Ischemic heart disease is the greatest cause of death in Western countries.
The deleterious effects of cardiac ischemia are ameliorated by ischemic preconditioning …

[PDF][PDF] The contemporary role of antioxidant therapy in attenuating liver ischemia‐reperfusion injury: A review

GK Glantzounis, HJ Salacinski, W Yang… - Liver …, 2005 - Wiley Online Library
Oxidative stress is an important factor in many pathological conditions such as inflammation,
cancer, ageing and organ response to ischemia‐reperfusion. Humans have developed a …

Systematic review of oxidative stress associated with pneumoperitoneum

T Sammour, A Mittal, BPT Loveday… - Journal of British …, 2009 - academic.oup.com
Background There have been several reports of ischaemic complications after routine
laparoscopy. The aim of this review was to investigate the relationship between this …