Bioprospecting sponge-associated microbes for antimicrobial compounds

AAG Indraningrat, H Smidt, D Sipkema - Marine drugs, 2016 - mdpi.com
Sponges are the most prolific marine organisms with respect to their arsenal of bioactive
compounds including antimicrobials. However, the majority of these substances are …

Exploring bacteria-induced growth and morphogenesis in the green macroalga order Ulvales (Chlorophyta)

T Wichard - Frontiers in plant science, 2015 - frontiersin.org
Green macroalgae, such as Ulvales, lose their typical morphology completely when grown
under axenic conditions or in the absence of the appropriate microbiome. As a result, slow …

Ecological and biotechnological importance of secondary metabolites produced by coral‐associated bacteria

F Modolon, AR Barno, HDM Villela… - Journal of Applied …, 2020 - academic.oup.com
Symbiotic relationships between corals and their associated micro‐organisms are essential
to maintain host homeostasis. Coral‐associated bacteria (CAB) can have different beneficial …

Shedding light on the composition of extreme microbial dark matter: alternative approaches for culturing extremophiles

J Schultz, F Modolon, RS Peixoto… - Frontiers in …, 2023 - frontiersin.org
More than 20,000 species of prokaryotes (less than 1% of the estimated number of Earth's
microbial species) have been described thus far. However, the vast majority of microbes that …

Culturing the uncultured microbial majority in activated sludge: a critical review

Y Zhang, T Zhang - Critical Reviews in Environmental Science and …, 2023 - Taylor & Francis
Activated sludge is a widely applied wastewater treatment process that mainly uses
suspended microbial flocs to remove pollutants in wastewater. With the characteristics of …

Next-generation drug discovery to combat antimicrobial resistance

G Niu, W Li - Trends in biochemical sciences, 2019 - cell.com
The widespread emergence of antibiotic-resistant pathogens poses a severe threat to public
health. This problem becomes even worse with a coincident decline in the supply of new …

Actinobacteria and myxobacteria—two of the most important bacterial resources for novel antibiotics

W Landwehr, C Wolf, J Wink - How to overcome the antibiotic crisis: facts …, 2016 - Springer
Bacteria have been by far the most promising resource for antibiotics in the past decades
and will in all undoubtedly remain an important resource of innovative bioactive natural …

Biological and chemical diversity of ascidian-associated microorganisms

L Chen, JS Hu, JL Xu, CL Shao, GY Wang - Marine drugs, 2018 - mdpi.com
Ascidians are a class of sessile filter-feeding invertebrates, that provide unique and fertile
niches harboring various microorganisms, such as bacteria, actinobacteria, cyanobacteria …

Renewed interests in the discovery of bioactive actinomycete metabolites driven by emerging technologies

J Ossai, B Khatabi, SE Nybo… - Journal of applied …, 2022 - Wiley Online Library
Actinomycetes are prolific sources of bioactive molecules. Traditional workflows including
bacterial isolation, fermentation, metabolite identification and structure elucidation have …

Genomic blueprints of sponge-prokaryote symbiosis are shared by low abundant and cultivatable Alphaproteobacteria

E Karimi, T Keller-Costa, BM Slaby, CJ Cox… - Scientific reports, 2019 - nature.com
Marine sponges are early-branching, filter-feeding metazoans that usually host complex
microbiomes comprised of several, currently uncultivatable symbiotic lineages. Here, we use …