Rituximab is an established therapy in children with idiopathic nephrotic syndrome to
sustain short-to medium-term disease remission and avoid steroid toxicities. Recent trials …

Immunosuppressants are commonly used as steroid-sparing agents in childhood idiopathic
nephrotic syndrome (NS) to induce and sustain remissions. These drugs have narrow …

Background Sequential rituximab (RTX) administration has emerged as an important
strategy to sustain remission of disease in patients with difficult-to-treat nephrotic syndrome …

Minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) are
glomerulopathies associated with nephrotic syndrome. Primary forms of these diseases are …

Background Despite the fact that rituximab (RTX)-associated adverse events may be
relatively frequent in younger patients, recent studies have reported RTX as a suitable first …

To the Editor, Nephrotic syndrome (NS), characterized by a triad of massive proteinuria,
generalized oedema and hypoalbuminemia, is a leading cause of chronic kidney disease …

Objectives: Prolonged use of corticosteroids induced complicated course in children with
steroid-dependent nephrotic syndrome (SDNS), and the use of tacrolimus, a first-line …

背景: 近20 多年来利妥昔单抗(RTX) 应用于儿童激素敏感型肾病综合征(SSNS)
的治疗较其他免疫抑制剂有更好的疗效, 但仍需要积累不良事件的报告情况. 目的 …

背景: 权威指南和共识均推荐将利妥昔单抗(RTX) 应用于儿童激素敏感型肾病综合征(SSNS)
中频复发/激素依赖肾病综合征(FRNS/SDNS) 的治疗, 但仍存在临床适应证不统一 …

摘要目的: 探讨原发性肾病综合征(PNS) 患儿经他克莫司联合泼尼松治疗后肾功能及免疫功能
变化情况. 方法: 采用随机数字表法将于2018 年6 月~ 2022 年7 月在河北省儿童医院接受治疗的 …