[HTML][HTML] Neutralizing monoclonal antibodies for treatment of COVID-19

PC Taylor, AC Adams, MM Hufford… - Nature Reviews …, 2021 - nature.com
Several neutralizing monoclonal antibodies (mAbs) to severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) have been developed and are now under evaluation in clinical …

[PDF][PDF] Adaptive immunity to SARS-CoV-2 and COVID-19

A Sette, S Crotty - Cell, 2021 - cell.com
The adaptive immune system is important for control of most viral infections. The three
fundamental components of the adaptive immune system are B cells (the source of …

Assessing transmissibility of SARS-CoV-2 lineage B. 1.1. 7 in England

E Volz, S Mishra, M Chand, JC Barrett, R Johnson… - Nature, 2021 - nature.com
Abstract The SARS-CoV-2 lineage B. 1.1. 7, designated variant of concern (VOC) 202012/01
by Public Health England, was first identified in the UK in late summer to early autumn 2020 …

mRNA vaccination boosts cross-variant neutralizing antibodies elicited by SARS-CoV-2 infection

L Stamatatos, J Czartoski, YH Wan, LJ Homad, V Rubin… - Science, 2021 - science.org
Emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have
raised concerns about resistance to neutralizing antibodies elicited by previous infection or …

Estimated transmissibility and impact of SARS-CoV-2 lineage B. 1.1. 7 in England

NG Davies, S Abbott, RC Barnard, CI Jarvis… - Science, 2021 - science.org
INTRODUCTION Several novel variants of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), the virus that causes COVID-19, emerged in late 2020. One of these, Variant …

Emergence and rapid spread of a new severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) lineage with multiple spike mutations in South Africa

H Tegally, E Wilkinson, M Giovanetti, A Iranzadeh… - medrxiv, 2020 - medrxiv.org
Continued uncontrolled transmission of the severe acute respiratory syndrome-related
coronavirus 2 (SARS-CoV-2) in many parts of the world is creating the conditions for …

Transmission of SARS-CoV-2 Lineage B. 1.1. 7 in England: Insights from linking epidemiological and genetic data

E Volz, S Mishra, M Chand, JC Barrett, R Johnson… - MedRxiv, 2021 - medrxiv.org
Abstract The SARS-CoV-2 lineage B. 1.1. 7, now designated Variant of Concern 202012/01
(VOC) by Public Health England, originated in the UK in late Summer to early Autumn 2020 …

[PDF][PDF] Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B. 1.1. 7

B Meng, SA Kemp, G Papa, R Datir, IATM Ferreira… - Cell reports, 2021 - cell.com
We report severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike ΔH69/V70
in multiple independent lineages, often occurring after acquisition of receptor binding motif …

[HTML][HTML] SARS-CoV-2 variant B. 1.1. 7 is susceptible to neutralizing antibodies elicited by ancestral spike vaccines

X Shen, H Tang, C McDanal, K Wagh, W Fischer… - Cell host & …, 2021 - cell.com
All current vaccines for COVID-19 utilize ancestral SARS-CoV-2 spike with the goal of
generating protective neutralizing antibodies. The recent emergence and rapid spread of …

Spread of a SARS-CoV-2 variant through Europe in the summer of 2020

EB Hodcroft, M Zuber, S Nadeau, TG Vaughan… - Nature, 2021 - nature.com
Following its emergence in late 2019, the spread of SARS-CoV-2, has been tracked by
phylogenetic analysis of viral genome sequences in unprecedented detail,–. Although the …