NKG2D is an activating receptor expressed on the surface of natural killer (NK) cells, CD8+
T cells, and subsets of CD4+ T cells, invariant NKT cells (iNKT), and γδ T cells. In humans …

Human cytomegalovirus (HCMV) infection induces both innate immune responses including
Natural Killer cells as well as adaptive humoral and cell mediated (CD4+ helper, CD8+ …

During human CMV infection, there is a preferential expansion of natural killer (NK) cells
expressing the activating CD94–NKG2C receptor complex, implicating this receptor in the …

Major mechanisms for the recognition of pathogens by immune cells have evolved to
employ classical and non-classical major histocompatibility complex class I (MHC I) …

The activating natural killer group 2 member D (NKG 2 D) receptor is expressed on NK cells,
cytotoxic T cells and additional T cell subsets. Ligands for human NKG 2 D comprise two …

Human cytomegalovirus (HCMV) is a ubiquitous double-stranded DNA virus belonging to
the β-subgroup of the herpesvirus family. After the initial infection, the virus establishes …

Human cytomegalovirus (HCMV) represents a prototypic pathogenic member of the β‐
subgroup of the herpesvirus family. A range of HCMV features like its lytic replication in …

Abstract γδT cells are a conserved population of innate lymphocytes with diverse structural
and functional heterogeneity that participate in various immune responses during tumor …

During the first trimester of pregnancy the uterus is massively infiltrated by decidual natural
killer cells (dNK). These cells are not killers, but they rather provide a microenvironment that …

NKG2D plays a major role in controlling immune responses through the regulation of natural
killer (NK) cells, αβ and γδ T-cell function. This activating receptor recognizes eight distinct …