Disassembly of layer-by-layer films of plasmid DNA and reducible TAT polypeptide

J Blacklock, H Handa, DS Manickam, G Mao… - Biomaterials, 2007 - Elsevier
This paper reports the disassembly of layer-by-layer (LbL) films of plasmid DNA and a
reducible cationic polypeptide. To utilize a reducing microenvironment of cellular plasma …

Impact of the nature, size and chain topologies of carbohydrate–phosphorylcholine polymeric gene delivery systems

M Ahmed, M Jawanda, K Ishihara, R Narain - Biomaterials, 2012 - Elsevier
With the recent significant advances in the field polymer chemistry, it is now possible to
produce well-defined and non-toxic cationic polymers with advanced molecular structures of …

Mixed polyplex micelles with thermoresponsive and lysine-based zwitterionic shells derived from two poly (vinyl amine)-based block copolymers

R Kanto, R Yonenuma, M Yamamoto, H Furusawa… - Langmuir, 2021 - ACS Publications
Two series of poly (vinyl amine)(PVAm)-based block copolymers with zwitterionic and
thermoresponsive segments were synthesized by the reversible addition–fragmentation …

Well-controlled cationic water-soluble phospholipid polymer− DNA nanocomplexes for gene delivery

M Ahmed, N Bhuchar, K Ishihara… - Bioconjugate …, 2011 - ACS Publications
The facile synthesis of biocompatible and nontoxic gene delivery vectors has been the focus
of research in recent years due to the high potential in treating genetic diseases. 2 …

Electrostatic layer-by-layer self-assembly of poly (carboxybetaine) s: Role of zwitterions in film growth

E Kharlampieva, VA Izumrudov, SA Sukhishvili - Macromolecules, 2007 - ACS Publications
We report on self-assembly of a weak zwitterionic polymer poly (carboxybetaine), PCB5
within a polyelectrolyte multilayer film. Multilayer growth and ionization of carboxylic groups …

Scanning force microscopy as applied to conformational studies in macromolecular research

MO Gallyamov - Macromolecular rapid communications, 2011 - Wiley Online Library
The modern state of SFM research on polymer nano‐objects including single chains is
discussed in comparison with other similar high‐resolution microscopy techniques. The …

Dendritic star polymers for efficient DNA binding and stimulus-dependent DNA release

M Yin, K Ding, RA Gropeanu, J Shen, R Berger… - …, 2008 - ACS Publications
Water-soluble core− shell star polymers consisting of a dendritic polyphenylene core and an
outer shell containing a defined number of amino groups have been synthesized via atom …

Versatile functionalization of gene vectors via different types of zwitterionic betaine species for serum-tolerant transfection

KM Xiu, NN Zhao, WT Yang, FJ Xu - Acta Biomaterialia, 2013 - Elsevier
For ideal polymeric gene vectors, their serum stability is of crucial importance. Polycation
vectors usually suffer from colloidal aggregation, which makes them easily cleared from the …

Nanostructure of polyplexes formed between cationic diblock copolymer and antisense oligodeoxynucleotide and its influence on cell transfection efficiency

XB Zhao, F Pan, ZQ Zhang, C Grant, YH Ma… - …, 2007 - ACS Publications
Although various cationic polymers have been used to condense anionically charged DNA
to improve their transfection efficiency, there is still a lack of fundamental understanding …

Synthesis of diblock/statistical cationic glycopolymers with pendant galactose and lysine moieties: Gene delivery application and intracellular behaviors

J Sun, R Sheng, T Luo, Z Wang, H Li… - Journal of Materials …, 2016 - pubs.rsc.org
A new series of cationic block copolymers PHML-b-PMAGal and statistical copolymers P
(HML-st-MAGal) with pendant natural galactose and (L-)-lysine moieties were prepared via …