Scanning probe microscopy in the field of drug delivery

YTA Turner, CJ Roberts, MC Davies - Advanced drug delivery reviews, 2007 - Elsevier
The scanning probe microscopes (SPMs) are a group of powerful surface sensitive
instruments which when used complimentarily with traditional analytical techniques can …

Synthesis of diblock/statistical cationic glycopolymers with pendant galactose and lysine moieties: Gene delivery application and intracellular behaviors

J Sun, R Sheng, T Luo, Z Wang, H Li… - Journal of materials …, 2016 - pubs.rsc.org
A new series of cationic block copolymers PHML-b-PMAGal and statistical copolymers P
(HML-st-MAGal) with pendant natural galactose and (L-)-lysine moieties were prepared via …

Nanostructure of polyplexes formed between cationic diblock copolymer and antisense oligodeoxynucleotide and its influence on cell transfection efficiency

XB Zhao, F Pan, ZQ Zhang, C Grant, YH Ma… - …, 2007 - ACS Publications
Although various cationic polymers have been used to condense anionically charged DNA
to improve their transfection efficiency, there is still a lack of fundamental understanding …

Drug carriers based on highly protein-resistant materials for prolonged in vivo circulation time

R Liu, Y Li, Z Zhang, X Zhang - Regenerative Biomaterials, 2015 - academic.oup.com
Long-circulating drug carriers are highly desirable in drug delivery system. However,
nonspecific protein adsorption leaves a great challenge in drug delivery of intravenous …

Dynamics of nucleic acid/cationic polymer complexation and disassembly under biologically simulated conditions using in situ atomic force microscopy

MS Shim, X Wang, R Ragan… - Microscopy research and …, 2010 - Wiley Online Library
Elucidating dynamic morphological changes of gene‐carrying vectors and their nucleic acid
release under varying intracellular conditions has been a technical challenge. Atomic force …

Photoinduced atom transfer radical polymerization in a polar solvent to synthesize a water-soluble poly (2-methacryloyloxyethyl phosphorylcholine) and its block-type …

S Chantasirichot, Y Inoue, K Ishihara - Polymer, 2015 - Elsevier
Photoinduced atom transfer radical polymerization (ATRP) has promising applications
because it requires small amounts of transition metal catalysts and low temperatures, and …

Synthesis and characterization of steroidal heterocyclic compounds, DNA condensation and molecular docking studies and their in vitro anticancer and …

A Ali, M Asif, H Khanam, A Mashrai, MA Sherwani… - RSC …, 2015 - pubs.rsc.org
A facile, convenient and efficient approach for the synthesis of a new series of steroidal
heterocyclic compounds (4–12) by reacting a mixture of compounds (1e–3e) with o …

Controlling fusion and aggregation in polymersome dispersions

TP Smart, C Fernyhough, AJ Ryan… - Macromolecular rapid …, 2008 - Wiley Online Library
The effects of addition of poly (ethylene oxide)(PEO) to poly (ethylene oxide) 16‐block‐poly
(butylene oxide) 22 (EB1) polymersome dispersions has been studied. Aggregation and …

[HTML][HTML] Naturally occurring branched-chain polyamines induce a crosslinked meshwork structure in a giant DNA

A Muramatsu, Y Shimizu, Y Yoshikawa… - The Journal of …, 2016 - pubs.aip.org
We studied the effect of branched-chain polyamines on the folding transition of genome-
sized DNA molecules in aqueous solution by the use of single-molecule observation with …

Surface modification of microspheres with steric stabilizing and cationic polymers for gene delivery

OR Davies, L Head, D Armitage, EA Pearson… - Langmuir, 2008 - ACS Publications
In this paper, we describe surface modification of poly (d, l-lactide-co-glycolide)(PLG)
microspheres, intended for DNA vaccine application, with two functionalities: a steric …