Novel cyclen-based linear polymer as a high-affinity binding material for DNA condensation
YZ Xiang, N Wang, J Zhang, K Li, ZW Zhang… - Science in China Series …, 2009 - Springer
A novel cyclen-based linear polyamine (POGEC) was designed and synthesized from the
reaction between 1, 3-propanediol diglycidyl ether and 1, 7-bis (diethoxyphosphory)-1, 4, 7 …
reaction between 1, 3-propanediol diglycidyl ether and 1, 7-bis (diethoxyphosphory)-1, 4, 7 …
Bioresponsive polyplexes and micelleplexes
C Alexander, F Fernandez Trillo - 2013 - books.rsc.org
The delivery of therapeutic biomacromolecules such as nucleic acids (NAs) is problematic
for many reasons, not least of which is their size. While most therapeutic proteins and …
for many reasons, not least of which is their size. While most therapeutic proteins and …
[HTML][HTML] 磷酸胆碱聚合物MPC30-DEA70 负载转化生长因子β1AS-ODN 转染心肌细胞
杨煜， 张敏， 徐建荣， 林雪烽， 赵侠， 王志荣， 曹希传… - 中国组织工程研究, 2015 - cjter.com
背景: 目前反义寡核苷酸的基因治疗已经拥有良好的应用前景, 但是反义寡核苷酸的相对分子
质量小却不容易入细胞并且易被核酸酶降解, 能否有效地穿过细胞膜且不被核酸酶降解从而与 …
质量小却不容易入细胞并且易被核酸酶降解, 能否有效地穿过细胞膜且不被核酸酶降解从而与 …
ДНК-полимерные комплексы для генной терапии
НА Касьяненко, ЛА Лысякова, БА Дрибинский… - … соединения. Серия С, 2012 - elibrary.ru
Методами атомной силовой микроскопии, низкоградиентной вискозиметрии,
динамического двойного лучепреломления, спектрофотометрии, кругового дихроизма …
динамического двойного лучепреломления, спектрофотометрии, кругового дихроизма …
Atomic force microscopy of DNA structure and interactions
NH Thomson - Applied Scanning Probe Methods VI: Characterization, 2007 - Springer
Scanning probe microscopes (SPMs) are perceived as tools central to the goals of the
burgeoning field known as nanotechnology. In the late 1950s, the physicist Richard …
burgeoning field known as nanotechnology. In the late 1950s, the physicist Richard …
磷酸胆碱聚合物载AT1 受体反义寡核苷酸对自发性高血压大鼠血压及心血管重构的影响
林雪烽， 徐建荣， 王霞， 冯辉， 张敏， 赵侠， 王志荣… - 齐齐哈尔医学院 …, 2012 - cqvip.com
目的探讨磷酸胆碱聚合物MPC30-DEA70 载AT1 受体反义寡核苷酸(AS-ODN)
对自发性高血压大鼠(SHR) 血压及心血管重构的影响. 方法将MPC30-DEA70 (N) 与FAM-AS …
对自发性高血压大鼠(SHR) 血压及心血管重构的影响. 方法将MPC30-DEA70 (N) 与FAM-AS …
Condensed multilamellar structure of a complex of DNA with an amphiphilic block copolymer
CJ Su, SW Yeh, WC Lai, HL Chen, MH Rahman… - Soft Matter, 2008 - pubs.rsc.org
Deoxyribonucleic acid (DNA) is an attractive building block for self-assembled
nanostructures, because the anionic phosphate group and the base moiety allow it to bind …
nanostructures, because the anionic phosphate group and the base moiety allow it to bind …
DNA 体外缩合的研究进展
张炳琦， 刘文广， 唐聪， 吉伟航， 姚康德 - 化学进展, 2006 - manu56.magtech.com.cn
摘要DNA 缩合不仅是自然界常见的生理现象, 也是非病毒载体介导基因转染的关键步骤.
了解DNA 体外缩合的性质与特征, 将有助于设计出高效的非病毒转基因载体 …
了解DNA 体外缩合的性质与特征, 将有助于设计出高效的非病毒转基因载体 …
Electrophoresis of a soft toroid of nonuniform structure
JP Hsu, CH Chou, CC Kuo, S Tseng, RM Wu - Colloids and Surfaces B …, 2012 - Elsevier
The electrophoresis of a nonuniformly structured soft particle is modeled theoretically by
considering an isolated soft toroid comprising a rigid core and a polyelectrolyte layer with …
considering an isolated soft toroid comprising a rigid core and a polyelectrolyte layer with …