[HTML][HTML] CCL2: An important cytokine in normal and pathological pregnancies: A review
Z Lin, JL Shi, M Chen, ZM Zheng, MQ Li… - Frontiers in …, 2023 - frontiersin.org
CC motif ligand 2 (CCL2), also known as monocytic chemotactic protein 1 (MCP-1), is an
integral chemotactic factor which recruits macrophages for the immune response. Together …
integral chemotactic factor which recruits macrophages for the immune response. Together …
[HTML][HTML] Innate and adaptive immune systems in physiological and pathological pregnancy
Simple Summary Pregnancy is a continually evolving process with many moving parts that
must be tightly regulated on both the maternal and fetal sides to ensure its success. A …
must be tightly regulated on both the maternal and fetal sides to ensure its success. A …
Deciphering maternal-fetal cross-talk in the human placenta during parturition using single-cell RNA sequencing
Labor is a complex physiological process requiring a well-orchestrated dialogue between
the mother and fetus. However, the cellular contributions and communications that facilitate …
the mother and fetus. However, the cellular contributions and communications that facilitate …
[HTML][HTML] Extracellular Vesicles-mediated recombinant IL-10 protects against ascending infection-associated preterm birth by reducing fetal inflammatory response
AK Kammala, A Mosebarger, E Radnaa… - Frontiers in …, 2023 - frontiersin.org
Background Fetal inflammatory response mediated by the influx of immune cells and
activation of pro-inflammatory transcription factor NF-κB in feto-maternal uterine tissues is …
activation of pro-inflammatory transcription factor NF-κB in feto-maternal uterine tissues is …
A key role for NLRP3 signaling in preterm labor and birth driven by the alarmin S100B
Preterm birth remains the leading cause of neonatal morbidity and mortality worldwide. A
substantial number of spontaneous preterm births occur in the context of sterile intra …
substantial number of spontaneous preterm births occur in the context of sterile intra …
[HTML][HTML] Repurposing existing drugs as a therapeutic approach for the prevention of preterm birth
In brief Preterm birth is the leading cause of perinatal morbidity and mortality; however,
current therapies offer limited efficacy to delay birth and improve neonatal outcomes. This …
current therapies offer limited efficacy to delay birth and improve neonatal outcomes. This …
Omega-3 fatty acid supply in pregnancy for risk reduction of preterm and early preterm birth
This clinical practice guideline on the supply of the omega-3 docosahexaenoic acid and
eicosapentaenoic acid in pregnant women for risk reduction of preterm birth and early …
eicosapentaenoic acid in pregnant women for risk reduction of preterm birth and early …
[HTML][HTML] Blockade of IL-6R prevents preterm birth and adverse neonatal outcomes
Background Preterm birth preceded by spontaneous preterm labour often occurs in the
clinical setting of sterile intra-amniotic inflammation (SIAI), a condition that currently lacks …
clinical setting of sterile intra-amniotic inflammation (SIAI), a condition that currently lacks …
[HTML][HTML] Roles of immune microenvironment in the female reproductive maintenance and regulation: novel insights into the crosstalk of immune cells
M Dai, Y Xu, G Gong, Y Zhang - Frontiers in immunology, 2023 - frontiersin.org
Female fertility decline is an accumulative consequence caused by complex factors, among
them, the disruption of the immune profile in female reproduction stands out as a crucial …
them, the disruption of the immune profile in female reproduction stands out as a crucial …
Immunosequencing and Profiling of T Cells at the Maternal–Fetal Interface of Women with Preterm Labor and Chronic Chorioamnionitis
T cells are implicated in the pathophysiology of preterm labor and birth, the leading cause of
neonatal morbidity and mortality worldwide. Specifically, maternal decidual T cells infiltrate …
neonatal morbidity and mortality worldwide. Specifically, maternal decidual T cells infiltrate …