Background Ovarian cancer (OC) is the most lethal gynecologic malignancy worldwide. One
of the main challenges in the management of OC is the late clinical presentation of disease …

In addition to mutations or aberrant expression in the protein-coding genes, mutations and
misregulation of noncoding RNAs, in particular long noncoding RNAs (lncRNA), appear to …

There is growing evidence that regions of the genome that cannot encode proteins play an
important role in diseases. These regions are usually transcribed into long non-coding …

Cancers of the female reproductive system include ovarian, uterine, vaginal, cervical and
vulvar cancers, which are termed gynecologic cancer. The emergence of long noncoding …

Long noncoding RNAs play a vital role in diverse biological processes such as embryonic
development, cell growth, and tumorigenesis. In this study, we report that LncRNA ANRIL …

Highlights•New roles of lncRNAs in ovarian cancer biology.•lncRNA as new prognostic
biomarkers for ovarian cancer patients.•Role of lncRNA in metastasis, recurrence and drug …

Long non-coding RNAs (lncRNAs) refer to functional cellular RNAs molecules longer than
200 nucleotides in length. Unlike microRNAs, which have been widely studied, little is …

Long non-coding RNAs (lncRNAs), a class of non-coding transcripts, have recently been
emerging with heterogeneous molecular actions, adding a new layer of complexity to gene …

Amongst the various gynecological malignancies affecting female health globally, ovarian
cancer is one of the predominant and lethal among all. The identification and functional …

Metastatic dissemination of epithelial ovarian cancer (EOC) predominantly occurs through
direct cell shedding from the primary tumor into the intra-abdominal cavity that is filled with …