Metabolic and vascular effect of the Mediterranean diet

A Tuttolomondo, I Simonetta, M Daidone… - International journal of …, 2019 - mdpi.com
Several studies indicated how dietary patterns that were obtained from nutritional cluster
analysis can predict disease risk or mortality. Low-grade chronic inflammation represents a …

Ceramides are fuel gauges on the drive to cardiometabolic disease

JL Wilkerson, SM Tatum, WL Holland… - Physiological …, 2024 - journals.physiology.org
Ceramides are signals of fatty acid excess that accumulate when a cell's energetic needs
have been met and its nutrient storage has reached capacity. As these sphingolipids accrue …

Ceramides and risk of major adverse cardiovascular events: a meta-analysis of longitudinal studies

A Mantovani, C Dugo - Journal of Clinical Lipidology, 2020 - Elsevier
Background Recent cohort studies evaluated the association between some previously
identified high-risk ceramides [Cer (d18: 1/16: 0), Cer (d18: 1/18: 0), Cer (d18: 1/22: 0), Cer …

Ceramide and regulation of vascular tone

A Cogolludo, E Villamor, F Perez-Vizcaino… - International journal of …, 2019 - mdpi.com
In addition to playing a role as a structural component of cellular membranes, ceramide is
now clearly recognized as a bioactive lipid implicated in a variety of physiological functions …

Plasma levels of ceramides relate to ischemic stroke risk and clinical severity

Y Gui, Q Li, L Liu, P Zeng, RF Ren, ZF Guo… - Brain research …, 2020 - Elsevier
Recent studies have suggested that specific plasma ceramides are independently
associated with atherosclerosis and cardiovascular diseases, but it is currently unknown …

Associations between specific plasma ceramides and severity of coronary-artery stenosis assessed by coronary angiography

A Mantovani, S Bonapace, G Lunardi, G Canali… - Diabetes & …, 2020 - Elsevier
Aim Recent prospective studies have identified distinct plasma ceramides as strong
predictors of major adverse cardiovascular events in patients with established or suspected …

Association between increased plasma ceramides and chronic kidney disease in patients with and without ischemic heart disease

A Mantovani, G Lunardi, S Bonapace, C Dugo… - Diabetes & …, 2021 - Elsevier
Aim Plasma levels of certain ceramides are increased in patients with ischemic heart
disease (IHD). Many risk factors for IHD are also risk factors for chronic kidney disease …

Association of plasma ceramides with myocardial perfusion in patients with coronary artery disease undergoing stress myocardial perfusion scintigraphy

A Mantovani, S Bonapace, G Lunardi… - … and Vascular Biology, 2018 - Am Heart Assoc
Objective—It is known that specific plasma ceramides are associated with stress-induced
reversible myocardial perfusion defects in patients with established or suspected coronary …

Relation between plasma ceramides and cardiovascular death in chronic heart failure: a subset analysis of the GISSI‐HF trial

G Targher, G Lunardi, A Mantovani… - ESC Heart …, 2020 - Wiley Online Library
Aims Ceramides exert several biological activities that may contribute to the
pathophysiology of cardiovascular disease and heart failure (HF). The association between …

Mediterranean diet in the targeted prevention and personalized treatment of chronic diseases: evidence, potential mechanisms, and prospects

Y Xiao, X Xiao, X Zhang, D Yi, T Li, Q Hao, F Zhang… - EPMA Journal, 2024 - Springer
The prevalence of chronic diseases is currently a major public health issue worldwide and is
exploding with the population growth and aging. Dietary patterns are well known to play a …