Molecular Mechanisms Associated with Neurodegeneration of Neurotropic Viral Infection

P Wongchitrat, T Chanmee, P Govitrapong - Molecular Neurobiology, 2024 - Springer
Viral infections of the central nervous system (CNS) cause variable outcomes from acute to
severe neurological sequelae with increased morbidity and mortality. Viral neuroinvasion …

Gastrointestinal microbiota and metabolites possibly contribute to distinct pathogenicity of SARS-CoV-2 proto or its variants in rhesus monkeys

H Chen, J Wang, K Ding, J Xu, Y Yang, C Tang… - Gut …, 2024 - Taylor & Francis
Gastrointestinal (GI) infection is evidenced with involvement in COVID-19 pathogenesis
caused by SARS-CoV-2. However, the correlation between GI microbiota and the distinct …

Epigenetic memory of coronavirus infection in innate immune cells and their progenitors

JG Cheong, A Ravishankar, S Sharma, CN Parkhurst… - Cell, 2023 - cell.com
Inflammation can trigger lasting phenotypes in immune and non-immune cells. Whether and
how human infections and associated inflammation can form innate immune memory in …

A Mouse Model of MHV‐1 Virus Infection for Study of Acute and Long COVID Infection

AD Masciarella, DM Di Gregorio… - Current …, 2023 - Wiley Online Library
Abstract COVID‐19, caused by SARS‐CoV‐2, has had a significant global impact. While
vaccines and treatments have reduced severe cases and deaths, the long‐term effects are …

Epigenetic memory of COVID-19 in innate immune cells and their progenitors

JG Cheong - 2023 - search.proquest.com
Systemic inflammation may trigger innate immune memory and persistent changes in
hematopoietic cells through epigenetic mechanisms, though investigating these phenotypes …

TDP-43 Controls HIV-1 Viral Production and Virus Infectiveness

R Cabrera-Rodríguez, S Pérez-Yanes… - International journal of …, 2023 - mdpi.com
The transactive response DNA-binding protein (TARDBP/TDP-43) is known to stabilize the
anti-HIV-1 factor, histone deacetylase 6 (HDAC6). TDP-43 has been reported to determine …

Meta-analysis of the serum/plasma proteome identifies significant associations between COVID-19 with Alzheimer's/Parkinson's diseases

A Mahin, SP Soman, PK Modi, R Raju… - Journal of …, 2024 - Springer
In recent years, we have seen the widespread devastations and serious health
complications manifested by COVID-19 globally. Although we have effectively controlled the …

A murine model of post-acute neurological sequelae following SARS-CoV-2 variant infection

A Singh, A Adam, Aditi, BH Peng, X Yu, J Zou… - Frontiers in …, 2024 - frontiersin.org
Viral variant is one known risk factor associated with post-acute sequelae of COVID-19
(PASC), yet the pathogenesis is largely unknown. Here, we studied SARS-CoV-2 Delta …

Acute and Long COVID Intestinal Changes in an Experimental Model of Coronavirus in Mice

H Hussain, N Elumalai, N Sampath, N Shamaladevi… - Viruses, 2024 - mdpi.com
The COVID-19 pandemic, which emerged in early 2020, has had a profound and lasting
impact on global health, resulting in over 7.0 million deaths and persistent challenges. In …

SPIKENET: An Evidence-Based Therapy for Long COVID

N Elumalai, H Hussain, N Sampath, N Shamaladevi… - Viruses, 2024 - mdpi.com
The COVID-19 pandemic has been one of the most impactful events in our lifetime, caused
by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Multiple SARS-CoV-2 …