Although the existence of cancer stem cells (CSCs) was first proposed over 40 years ago,
only in the past decade have these cells been identified in hematological malignancies, and …

Nowadays, cancer has been a frequent disease, and the first or second most common cause
of death worldwide. Despite a better understanding of the biology of cancer cells, the …

Background Growing evidence suggests that cancer stem cells (CSCs) are responsible for
cancer initiation in tumors. Bach1 has been identified to contribute to several tumor …

Anti-angiogenesis-related therapies have become the standard care for patients with
advanced hepatocellular carcinoma (HCC), as HCC is a highly vascularized solid tumor …

Colorectal cancer (CRC) frequently metastasizes to the liver, a phenomenon that involves
the participation of transforming-growth-factor-β1 (TGFβ1). Blockade of the protumorigenic …

This textbook is designed to be a comprehensive assessment of current knowledge
regarding the surgical and general pathology of hepatobiliary tumors and tumor-like lesions …

Embryonic stem cells divide continuously and differentiate into organs through the
expression of specific transcription factors at specific time periods. Differentiated adult stem …

Lung cancer stem cells are a subpopulation of cells critical for lung cancer progression,
metastasis, and drug resistance. Thioridazine, a classical neurological drug, has been …

Glioblastoma multiforme (GBM) is a highly aggressive brain tumor, with dismal survival
outcomes. Recently, cancer stem cells (CSCs) have been demonstrated to play a role in …

[Frontiers in Bioscience E4, 1157-1169, January 1, 2012] 1157 Hepatocellular carcinoma stem
cells: origins and roles in hepatoca Page 1 [Frontiers in Bioscience E4, 1157-1169, January 1 …