[HTML][HTML] A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a respiratory
disease called coronavirus disease 2019 (COVID-19), the spread of which has led to a …
disease called coronavirus disease 2019 (COVID-19), the spread of which has led to a …
[HTML][HTML] Cathepsin L plays a key role in SARS-CoV-2 infection in humans and humanized mice and is a promising target for new drug development
MM Zhao, WL Yang, FY Yang, L Zhang… - Signal transduction and …, 2021 - nature.com
To discover new drugs to combat COVID-19, an understanding of the molecular basis of
SARS-CoV-2 infection is urgently needed. Here, for the first time, we report the crucial role of …
SARS-CoV-2 infection is urgently needed. Here, for the first time, we report the crucial role of …
[HTML][HTML] A mouse-adapted SARS-CoV-2 induces acute lung injury and mortality in standard laboratory mice
The SARS-CoV-2 pandemic has caused extreme human suffering and economic harm. We
generated and characterized a new mouse-adapted SARS-CoV-2 virus that captures …
generated and characterized a new mouse-adapted SARS-CoV-2 virus that captures …
Neuroinvasion of SARS-CoV-2 in human and mouse brain
Although COVID-19 is considered to be primarily a respiratory disease, SARS-CoV-2 affects
multiple organ systems including the central nervous system (CNS). Yet, there is no …
multiple organ systems including the central nervous system (CNS). Yet, there is no …
[HTML][HTML] Overview of immune response during SARS-CoV-2 infection: lessons from the past
After the 1918 flu pandemic, the world is again facing a similar situation. However, the
advancement in medical science has made it possible to identify that the novel infectious …
advancement in medical science has made it possible to identify that the novel infectious …
[HTML][HTML] Potential intestinal infection and faecal–oral transmission of SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to more than
200 countries and regions globally. SARS-CoV-2 is thought to spread mainly through …
200 countries and regions globally. SARS-CoV-2 is thought to spread mainly through …
Lessons learned 1 year after SARS-CoV-2 emergence leading to COVID-19 pandemic
KKW To, S Sridhar, KHY Chiu, DLL Hung… - Emerging microbes & …, 2021 - Taylor & Francis
Without modern medical management and vaccines, the severity of the Coronavirus
Disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome (SARS) …
Disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome (SARS) …
[HTML][HTML] Insights to SARS-CoV-2 life cycle, pathophysiology, and rationalized treatments that target COVID-19 clinical complications
Background Gaining further insights into SARS-CoV-2 routes of infection and the underlying
pathobiology of COVID-19 will support the design of rational treatments targeting the life …
pathobiology of COVID-19 will support the design of rational treatments targeting the life …
[HTML][HTML] Cellular host factors for SARS-CoV-2 infection
Abstract The coronavirus disease 2019 (COVID-19) pandemic has claimed millions of lives
and caused a global economic crisis. No effective antiviral drugs are currently available to …
and caused a global economic crisis. No effective antiviral drugs are currently available to …
Anosmia in COVID-19: underlying mechanisms and assessment of an olfactory route to brain infection
R Butowt, CS von Bartheld - The Neuroscientist, 2021 - journals.sagepub.com
In recent months it has emerged that the novel coronavirus—responsible for the COVID-19
pandemic—causes reduction of smell and taste in a large fraction of patients. The …
pandemic—causes reduction of smell and taste in a large fraction of patients. The …