The immune response to SARS-CoV-2 in people with HIV

MA Höft, WA Burgers, C Riou - Cellular & Molecular Immunology, 2024 - nature.com
This review examines the intersection of the HIV and SARS-CoV-2 pandemics. People with
HIV (PWH) are a heterogeneous group that differ in their degree of immune suppression …

The importance of measuring SARS-CoV-2-specific T-cell responses in an ongoing pandemic

L Petrone, A Sette, RD de Vries, D Goletti - Pathogens, 2023 - mdpi.com
Neutralizing antibodies are considered a correlate of protection against SARS-CoV-2
infection and severe COVID-19, although they are not the only contributing factor to …

Post-pandemic memory T cell response to SARS-CoV-2 is durable, broadly targeted, and cross-reactive to the hypermutated BA. 2.86 variant

R Nesamari, MA Omondi, R Baguma, MA Höft… - Cell host & …, 2024 - cell.com
Ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evolution has
given rise to recombinant Omicron lineages that dominate globally (XBB. 1), as well as the …

Vaccine development against tuberculosis before and after Covid-19

SHE Kaufmann - Frontiers in Immunology, 2023 - frontiersin.org
Coronavirus disease (Covid-19) has not only shaped awareness of the impact of infectious
diseases on global health. It has also provided instructive lessons for better prevention …

Broad protective RBD heterotrimer vaccines neutralize SARS-CoV-2 including Omicron sub-variants XBB/BQ. 1.1/BF. 7

Y Zhang, X Kang, S Liu, P Han, W Lei, K Xu… - PLoS …, 2023 - journals.plos.org
SARS-CoV-2 variants with severe immune evasion are a major challenge for COVID-19
prevention, especially the circulating Omicron XBB/BQ. 1.1/BF. 7 strains. Thus, the next …

Clearance of persistent SARS-CoV-2 associates with increased neutralizing antibodies in advanced HIV disease post-ART initiation

F Karim, C Riou, M Bernstein, Z Jule, G Lustig… - Nature …, 2024 - nature.com
SARS-CoV-2 clearance requires adaptive immunity but the contribution of neutralizing
antibodies and T cells in different immune states is unclear. Here we ask which adaptive …

[HTML][HTML] Principles and therapeutic applications of adaptive immunity

H Chi, M Pepper, PG Thomas - Cell, 2024 - cell.com
Adaptive immunity provides protection against infectious and malignant diseases. These
effects are mediated by lymphocytes that sense and respond with targeted precision to …

An updated review of epidemiological characteristics, immune escape, and therapeutic advances of SARS-CoV-2 Omicron XBB. 1.5 and other mutants

Z Liu, J Li, S Pei, Y Lu, C Li, J Zhu, R Chen… - Frontiers in Cellular …, 2023 - frontiersin.org
The rapid evolution of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
has led to the emergence of new variants with different genetic profiles, with important …

Cross-reactive humoral and CD4+ T cell responses to Mu and Gamma SARS-CoV-2 variants in a Colombian population

F Martel, J Cuervo-Rojas, J Ángel, B Ariza… - Frontiers in …, 2023 - frontiersin.org
The SARS CoV-2 antibody and CD4+ T cell responses induced by natural infection and/or
vaccination decline over time and cross-recognize other viral variants at different levels …

COVID-19 point-of-care tests can identify low-antibody individuals: In-depth immunoanalysis of boosting benefits in a healthy cohort

M Mallory, JE Munt, TM Narowski, I Castillo… - Science …, 2024 - science.org
The recommended COVID-19 booster vaccine uptake is low. At-home lateral flow assay
(LFA) antigen tests are widely accepted for detecting infection during the pandemic. Here …