BACKGROUND: The authors systematically reviewed the literature and conducted a pooled
analysis of studies on small renal masses who underwent active surveillance to identify the …

Purpose: Standard therapy for an enhancing renal mass is surgical. However, operative
treatment may not be plausible in all clinical circumstances. Data on the natural history of …

DETECTION of clinical stage 1 (7.0 cm) renal masses has increased in frequency and is
now a common clinical scenario for the practicing urologist. 1–4 These tumors are very …

BACKGROUND The incidence of renal cell carcinoma (RCC) is increasing, largely due to
the widespread use of cross‐sectional imaging. Most renal tumors are detected incidentally …

Despite substantial advances in the imaging-based diagnosis of renal masses, the
increased detection of incidental renal masses with cross-sectional imaging poses problems …

CONTEXT: The increasing incidence of localised renal cell carcinoma (RCC) over the last 3
decades and controversy over mortality rates have prompted reassessment of current …

Many aspects of the evolutionary process of tumorigenesis that are fundamental to cancer
biology and targeted treatment have been challenging to reveal, such as the divergence …

BACKGROUND. Kidney cancer's rising incidence is largely attributable to the increased
detection of small renal masses. Although surgery rates have paralleled this incidence trend …

Renal cell carcinoma (RCC) comprises approximately 3.8% of all new cancers in the
western world; the detection rate of RCC has been increasing in the past 10 years by …

Purpose: We investigated the natural history of incidentally discovered small renal cell
carcinomas (RCCs), and we evaluated growth rate, apoptosis, cell proliferation and …