Therapeutic strategies for COVID-19: progress and lessons learned
G Li, R Hilgenfeld, R Whitley, E De Clercq - Nature Reviews Drug …, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has stimulated tremendous
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …
Structural biology of SARS-CoV-2 and implications for therapeutic development
H Yang, Z Rao - Nature Reviews Microbiology, 2021 - nature.com
The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), is an unprecedented global health crisis. However, therapeutic options for …
(SARS-CoV-2), is an unprecedented global health crisis. However, therapeutic options for …
Molecular mechanism of interaction between SARS-CoV-2 and host cells and interventional therapy
Q Zhang, R Xiang, S Huo, Y Zhou, S Jiang… - Signal transduction and …, 2021 - nature.com
The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in an unprecedented setback …
syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in an unprecedented setback …
Rapid single-molecule detection of COVID-19 and MERS antigens via nanobody-functionalized organic electrochemical transistors
Abstract The coronavirus disease 2019 (COVID-19) pandemic has highlighted the need for
rapid and sensitive protein detection and quantification in simple and robust formats for …
rapid and sensitive protein detection and quantification in simple and robust formats for …
[HTML][HTML] Functional SARS-CoV-2-specific immune memory persists after mild COVID-19
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus is causing a
global pandemic, and cases continue to rise. Most infected individuals experience mildly …
global pandemic, and cases continue to rise. Most infected individuals experience mildly …
Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape
INTRODUCTION The global scale and rapid spread of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) pose unprecedented challenges to society, health care …
coronavirus 2 (SARS-CoV-2) pose unprecedented challenges to society, health care …
Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2
The SARS-CoV-2 virus is more transmissible than previous coronaviruses and causes a
more serious illness than influenza. The SARS-CoV-2 receptor binding domain (RBD) of the …
more serious illness than influenza. The SARS-CoV-2 receptor binding domain (RBD) of the …
SARS-CoV-2 antiviral therapy
The development of effective antiviral therapy for COVID-19 is critical for those awaiting
vaccination, as well as for those who do not respond robustly to vaccination. This review …
vaccination, as well as for those who do not respond robustly to vaccination. This review …
Linear epitope landscape of the SARS-CoV-2 Spike protein constructed from 1,051 COVID-19 patients
Y Li, M Ma, Q Lei, F Wang, W Hong, D Lai, H Hou, Z Xu… - Cell reports, 2021 - cell.com
To fully decipher the immunogenicity of the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) Spike protein, it is essential to assess which part is highly immunogenic in a …
(SARS-CoV-2) Spike protein, it is essential to assess which part is highly immunogenic in a …
Structure-function analyses of new SARS-CoV-2 variants B. 1.1. 7, B. 1.351 and B. 1.1. 28.1: clinical, diagnostic, therapeutic and public health implications
SARS-CoV-2 (Severe Acute Respiratory Syndrome-Coronavirus 2) has accumulated
multiple mutations during its global circulation. Recently, three SARS-CoV-2 lineages, B …
multiple mutations during its global circulation. Recently, three SARS-CoV-2 lineages, B …