Research Opportunities in the Treatment of Mitral Valve Prolapse: JACC Expert Panel

FN Delling, PA Noseworthy, DH Adams… - Journal of the American …, 2022 - jacc.org
In light of the adverse prognosis related to severe mitral regurgitation, heart failure, or
sudden cardiac death in a subset of patients with mitral valve prolapse (MVP), identifying …

The global burden of valvular heart disease: from clinical epidemiology to management

G Santangelo, F Bursi, A Faggiano… - Journal of Clinical …, 2023 - mdpi.com
Valvular heart disease is a leading cause of cardiovascular morbidity and mortality and a
major contributor of symptoms and functional disability. Knowledge of valvular heart disease …

EHRA expert consensus statement on arrhythmic mitral valve prolapse and mitral annular disjunction complex in collaboration with the ESC Council on valvular heart …

A Sabbag, B Essayagh, JDR Barrera, C Basso… - Europace, 2022 - academic.oup.com
Risk stratification scheme. Risk stratification aiming at assessing the risk of VAs and SCD in
patients with MVP, involving two phases based on the clinical and imaging context and the …

Mitral annular disjunction assessed using CMR imaging: insights from the UK biobank population study

D Zugwitz, K Fung, N Aung, E Rauseo… - Cardiovascular …, 2022 - jacc.org
Background Mitral annular disjunction is the atrial displacement of the mural mitral valve
leaflet hinge point within the atrioventricular junction. Said to be associated with malignant …

Myocardial fibrosis at cardiac MRI helps predict adverse clinical outcome in patients with mitral valve prolapse

S Figliozzi, G Georgiopoulos, PM Lopes, KB Bauer… - Radiology, 2023 - pubs.rsna.org
Background Patients with mitral valve prolapse (MVP) may develop adverse outcomes even
in the absence of mitral regurgitation or left ventricular (LV) dysfunction. Purpose To …

Mitral annular disjunction of degenerative mitral regurgitation: three-dimensional evaluation and implications for mitral repair

B Essayagh, F Mantovani, G Benfari, JF Maalouf… - Journal of the American …, 2022 - Elsevier
Background The dynamic consequences of mitral annular disjunction (MAD) on the mitral
apparatus and the left ventricle remain unclear and are crucial in the context of mitral …

Arrhythmic mitral valve prolapse and mitral annular disjunction: pathophysiology, risk stratification, and management

B Essayagh, A Sabbag, E El-Am… - European heart …, 2023 - academic.oup.com
Mitral valve prolapse (MVP) is the most frequent valve condition but remains a conundrum in
many aspects, particularly in regard to the existence and frequency of an arrhythmic form …

Imaging for the assessment of the arrhythmogenic potential of mitral valve prolapse

A Esposito, M Gatti, MG Trivieri, E Agricola, G Peretto… - European …, 2024 - Springer
Mitral valve prolapse (MVP) is the most common valve disease in the western world and
recently emerged as a possible substrate for sudden cardiac death (SCD). It is estimated an …

Ventricular arrhythmias in arrhythmic mitral valve syndrome—a prospective continuous long-term cardiac monitoring study

EW Aabel, M Chivulescu, ØH Lie, E Hopp… - Europace, 2023 - academic.oup.com
Aims Arrhythmic mitral valve syndrome is linked to life-threatening ventricular arrhythmias.
The incidence, morphology and methods for risk stratification are not well known. This …

Prevalence of mitral annulus disjunction and mitral valve prolapse in patients with idiopathic ventricular fibrillation

SA Groeneveld, FP Kirkels, MJ Cramer… - Journal of the …, 2022 - Am Heart Assoc
Background Idiopathic ventricular fibrillation (IVF) is diagnosed in patients with ventricular
fibrillation of which the origin is not identified after extensive evaluations. Recent studies …