COVID-19 complications: oxidative stress, inflammation, and mitochondrial and endothelial dysfunction

E Georgieva, J Ananiev, Y Yovchev… - International Journal of …, 2023 - mdpi.com
SARS-CoV-2 infection, discovered and isolated in Wuhan City, Hubei Province, China,
causes acute atypical respiratory symptoms and has led to profound changes in our lives …

Pro-inflammatory and anti-inflammatory interleukins in infectious diseases: A comprehensive review

AA Al-Qahtani, FS Alhamlan, AA Al-Qahtani - Tropical medicine and …, 2024 - mdpi.com
Interleukins (ILs) are signaling molecules that are crucial in regulating immune responses
during infectious diseases. Pro-inflammatory ILs contribute to the activation and recruitment …

[HTML][HTML] Enhanced fatty acid oxidation through metformin and baicalin as therapy for COVID-19 and associated inflammatory states in lung and kidney

V Miguel, C Rey-Serra, J Tituaña, B Sirera… - Redox Biology, 2023 - Elsevier
Progressive respiratory failure is the primary cause of death in the coronavirus disease 2019
(COVID-19) pandemic. It is the final outcome of the acute respiratory distress syndrome …

Iron accumulation and lipid peroxidation: implication of ferroptosis in diabetic cardiomyopathy

X Yan, Y Xie, H Liu, M Huang, Z Yang, D An… - Diabetology & Metabolic …, 2023 - Springer
Diabetic cardiomyopathy (DC) is a serious heart disease caused by diabetes. It is unrelated
to hypertension and coronary artery disease and can lead to heart insufficiency, heart failure …

Function and inhibition of P38 MAP kinase signaling: Targeting multiple inflammation diseases

J Wang, Y Liu, Y Gu, C Liu, Y Yang, X Fan… - Biochemical …, 2023 - Elsevier
Inflammation is a natural host defense mechanism that protects the body from pathogenic
microorganisms. A growing body of research suggests that inflammation is a key factor in …

Multi-target drugs for the treatment of cognitive impairment and fatigue in post-COVID syndrome: focus on Ginkgo biloba and Rhodiola rosea

JK Mueller, WE Müller - Journal of Neural Transmission, 2024 - Springer
Cognitive impairment, depression and (mental) fatigue represent the most frequent
neuropsychiatric symptoms of the post-COVID syndrome. Neuroinflammation, oxidative …

Unveiling COVID-19 secrets: Harnessing Cytokines as powerful biomarkers for diagnosis and predicting severity

B Wolszczak-Biedrzycka, J Dorf… - Journal of …, 2023 - Taylor & Francis
Introduction In coronavirus disease (COVID-19), inflammation takes center stage, with a
cascade of cytokines released, contributing to both inflammation and lung damage. The …

Serum Level of Ceruloplasmin, Angiotensin-Converting Enzyme and Transferrin as Markers of Severity in SARS-CoV-2 Infection in Patients with Type 2 Diabetes

PA Reștea, Ș Țigan, LG Vicaș, L Fritea, E Marian… - Microbiology …, 2023 - mdpi.com
The aim of this study was to analyze other possible new markers of severity, at hospital
admission, that can be assessed in patients with type 2 diabetes and a SARS-CoV-2 (severe …

Tocilizumab as a potential adjunctive therapy to corticosteroids in cryptococcal post-infectious inflammatory response syndrome (PIIRS): a report of two cases

JC Hargarten, SH Anjum, K Ssebambulidde… - Journal of Clinical …, 2023 - Springer
Purpose Non-HIV cryptococcal meningoencephalitis (CM) in previously healthy individuals
is often complicated by a post-infectious inflammatory response syndrome (c-PIIRS) …

Exploring the role of tryptophanyl-tRNA synthetase and associations with inflammatory markers and clinical outcomes in COVID-19 patients: A case-control study

N Najimi, H Zahednasab, M Farahmand… - Microbial …, 2023 - Elsevier
Tryptophanyl-tRNA synthetase (WRS) is a critical enzyme involved in protein synthesis,
responsible for charging tRNA with the essential amino acid tryptophan. Recent studies …