Measuring specific gene transcription in noninvasive clinical samples has the potential to
become an important and standard tool to monitor alloimmune-mediated injury in kidney …

Background Although improved understanding and assessment of organ rejection
significantly contribute to long-term allograft survival after kidney transplantation, reliable …

Acute rejection (AR) of corneal transplants (CT) has a profound effect on subsequent graft
survival but detailed immunological studies in human CT recipients are lacking. In this multi …

Objective: To test the hypothesis that gene expression profiling in peripheral blood from
patients who have undergone kidney transplantation (KT) will provide mechanistic insights …

Background In transplant medicine, clinical decision making largely relies on histology of
biopsy specimens. However, histology suffers from low specificity, sensitivity, and …

Assessing human immune response remains a challenge as it involves multiple cell types in
specific tissues. The use of microarray-based expression profiling as a tool for assessing the …

Although the first 50 years of renal transplantation were marked by great advances in
immunosuppressive therapies, the past decade has been marked by an unprecedented …

This review is focused on present and future biomarkers, along with pharmacogenomics
used in clinical practice for kidney transplantation. It aims to highlight biomarkers that could …

One important use of genome-wide transcriptional profiles is to identify relationships
between transcription levels and patient outcomes. These translational insights can guide …

We determined peripheral blood (PB) and biopsy (Bx) RNA expression signatures in a
Brazilian and US cohort of kidney transplant patients. Phenotypes assigned by precise …