[HTML][HTML] Duration of BA. 5 neutralization in sera and nasal swabs from SARS-CoV-2 vaccinated individuals, with or without omicron breakthrough infection

D Planas, I Staropoli, F Porot, F Guivel-Benhassine… - Med, 2022 - cell.com
Summary Background Since early 2022, Omicron BA. 1 has been eclipsed by BA. 2, which
was in turn outcompeted by BA. 5, which displays enhanced antibody escape properties …

[HTML][HTML] Vagus nerve dysfunction in the post–COVID-19 condition: a pilot cross-sectional study

G Lladós, M Massanella, R Coll-Fernández… - Clinical Microbiology …, 2024 - Elsevier
Objectives The post–COVID-19 condition (PCC) is a disabling syndrome affecting at least
5%–10% of subjects who survive COVID-19. SARS-CoV-2 mediated vagus nerve …

The aged microenvironment impairs BCL6 and CD40L induction in CD4+ T follicular helper cell differentiation

JS Fisher, I Adán‐Barrientos, NR Kumar… - Aging …, 2024 - Wiley Online Library
Weakened germinal center responses by the aged immune system result in diminished
immunity against pathogens and reduced efficacy of vaccines. Prolonged contacts between …

Efficacy of SARS-CoV-2 vaccination in patients with monoclonal gammopathies: a cross sectional study

E Abella, E Pradenas, F Muñoz-Lopez… - Life Science …, 2022 - life-science-alliance.org
SARS-CoV-2 vaccination is the most effective strategy to protect individuals with
haematologic malignancies against severe COVID-19, while eliciting limited vaccine …

Immunisation efficacy of a stabilised SARS-CoV-2 spike glycoprotein in two geriatric animal models

C Usai, E Ainsua-Enrich, VU Gales, E Pradenas… - npj Vaccines, 2024 - nature.com
Age is associated with reduced efficacy of vaccines and linked to higher risk of severe
COVID-19. Here we determined the impact of ageing on the efficacy of a SARS-CoV-2 …

A multinational, phase 2, randomised, adaptive protocol to evaluate immunogenicity and reactogenicity of different COVID-19 vaccines in adults≥ 75 already …

JM Neuhann, J Stemler, A Carcas, J Frías-Iniesta… - Trials, 2022 - Springer
Background In the ongoing COVID-19 pandemic, advanced age is a risk factor for a severe
clinical course of SARS-CoV-2 infection. Thus, older people may benefit in particular from …

MMS19 and IFIH1 Host Genetic Variants Associate with SARS-CoV-2 Infection in Elderly Residents of Long-Term Care Facilities

S Franco, D Palacín, JM Bonet-Simó, M del Mar Isnard… - 2024 - preprints.org
Abstract The Coronavirus disease 2019 (COVID-19) pandemic has significantly affected
older adults. Identifying host COVID-19 susceptibility genes in elderly populations remains a …

Impact of hybrid immunity booster vaccination and Omicron breakthrough infection on SARS-CoV-2 VOCs cross-neutralization

E Pradenas, S Marfil, V Urrea, T Pidkova… - Iscience, 2023 - cell.com
The elicitation of cross-variant neutralizing antibodies against SARS-CoV-2 represents a
major goal for current COVID-19 vaccine strategies. Additionally, natural infection may also …

[HTML][HTML] STUDY PROTOCOL A multinational, phase 2, randomised, adaptive protocol to evaluate immunogenicity and reactogenicity of different COVID-19 vaccines in …

JM Neuhann, J Stemler, A Carcas, J Frías-Iniesta… - 2022 - europepmc.org
Background: In the ongoing COVID-19 pandemic, advanced age is a risk factor for a severe
clinical course of SARS-CoV-2 infection. Thus, older people may benefit in particular from …

Efficacy of SARS-CoV-2 vaccination in patients with monoclonal gammopathies: A cross sectional study

E Abella Monreal, F Garcia Pallarols… - Life Sci Alliance …, 2022 - repositori.upf.edu
SARS-CoV-2 vaccination is the most effective strategy to protect individuals with
haematologic malignancies against severe COVID-19, while eliciting limited vaccine …