Adopting Mechanistic Molecular Biology Approaches in Exposome Research for Causal Understanding
AL Foreman, B Warth, EVS Hessel… - Environmental …, 2024 - ACS Publications
Through investigating the combined impact of the environmental exposures experienced by
an individual throughout their lifetime, exposome research provides opportunities to …
an individual throughout their lifetime, exposome research provides opportunities to …
What Causes Premature Coronary Artery Disease?
A Le, H Peng, D Golinsky, M Di Scipio, R Lali… - Current Atherosclerosis …, 2024 - Springer
Abstract Purpose of Review This review provides an overview of genetic and non-genetic
causes of premature coronary artery disease (pCAD). Recent Findings pCAD refers to …
causes of premature coronary artery disease (pCAD). Recent Findings pCAD refers to …
[HTML][HTML] A method to estimate the contribution of rare coding variants to complex trait heritability
It has been postulated that rare coding variants (RVs; MAF< 0.01) contribute to the “missing”
heritability of complex traits. We developed a framework, the Rare variant heritability …
heritability of complex traits. We developed a framework, the Rare variant heritability …
[HTML][HTML] Distinct explanations underlie gene-environment interactions in the UK Biobank
A Durvasula, AL Price - medRxiv, 2023 - ncbi.nlm.nih.gov
The role of gene-environment (GxE) interaction in disease and complex trait architectures is
widely hypothesized, but currently unknown. Here, we apply three statistical approaches to …
widely hypothesized, but currently unknown. Here, we apply three statistical approaches to …
Genetic Determinants of Vascular Dementia
Vascular dementia (VaD) is a prevalent form of cognitive impairment with underlying
vascular etiology. In this review, we examine recent genetic advancements in our …
vascular etiology. In this review, we examine recent genetic advancements in our …
The drivers of intraspecific trait variation and their implications for future tree productivity and survival
M Blumstein - American Journal of Botany, 2024 - Wiley Online Library
Forests are facing unprecedented levels of stress from pest and disease outbreaks,
disturbance, fragmentation, development, and a changing climate. These selective agents …
disturbance, fragmentation, development, and a changing climate. These selective agents …