Exploring the Nutraceutical Potential of Dried Pepper Capsicum annuum L. on Market from Altino in Abruzzo Region

A Della Valle, MP Dimmito, G Zengin, S Pieretti… - Antioxidants, 2020 - mdpi.com
Sweet pepper is a typical type of Capsicum annuum from Abruzzo region, recognized as a
traditional and local product, traditionally cultivated in the town of Altino (Abruzzo region …

A novel insight into the immune-related interaction of inflammatory cytokines in Benign prostatic hyperplasia

X Naiyila, J Li, Y Huang, B Chen, M Zhu, J Li… - Journal of Clinical …, 2023 - mdpi.com
Benign prostatic hyperplasia (BPH) is a common male condition that impacts many men's
quality of life by generating lower urinary tract symptoms (LUTS). In recent years …

Natural products for the management of castration-resistant prostate cancer: Special focus on nanoparticles based studies

RK Singla, CS Sai, H Chopra, S Behzad… - Frontiers in cell and …, 2021 - frontiersin.org
Prostate cancer is the most common type of cancer among men and the second most
frequent cause of cancer-related mortality around the world. The progression of advanced …

Targeting the redox imbalance in mitochondria: A novel mode for cancer therapy

S Mani, G Swargiary, SJ Ralph - Mitochondrion, 2022 - Elsevier
Abstract Changes in reactive oxygen species (ROS) levels affect many aspects of cell
behavior. During carcinogenesis, moderate ROS production modifies gene expression to …

Heat shock factor 1 directly regulates transsulfuration pathway to promote prostate cancer proliferation and survival

JS Hauck, D Moon, X Jiang, ME Wang, Y Zhao… - Communications …, 2024 - nature.com
There are limited therapeutic options for patients with advanced prostate cancer (PCa). We
previously found that heat shock factor 1 (HSF1) expression is increased in PCa and is an …

The etiology and pathophysiology genesis of benign prostatic hyperplasia and prostate cancer: a new perspective

TJ Phua - Medicines, 2021 - mdpi.com
Background: The etiology of benign prostatic hyperplasia and prostate cancer are unknown,
with ageing being the greatness risk factor. Methods: This new perspective evaluates the …

[HTML][HTML] Targeting benign prostate hyperplasia treatments: AR/TGF-β/NOX4 inhibition by apocynin suppresses inflammation and proliferation

BR Jin, HJ Kim, JH Na, WK Lee, HJ An - Journal of Advanced Research, 2024 - Elsevier
Abstract Introduction Apocynin (Apo), an NADPH oxidase (NOX) inhibitor, has been widely
used to treat various inflammatory diseases. However, the therapeutic effects of Apo on …

Oxidative stress links aging‐associated cardiovascular diseases and prostatic diseases

MJ Zhao, S Yuan, H Zi, JM Gu, C Fang… - … Medicine and Cellular …, 2021 - Wiley Online Library
The incidence of chronic aging‐associated diseases, especially cardiovascular and
prostatic diseases, is increasing with the aging of society. Evidence indicates that …

piR-31470 epigenetically suppresses the expression of glutathione S-transferase pi 1 in prostate cancer via DNA methylation

L Zhang, X Meng, C Pan, F Qu, W Gan, Z Xiang, X Han… - Cellular signalling, 2020 - Elsevier
Inactivation of glutathione S-transferase pi 1 (GSTP1) via hypermethylation is an early and
common event in prostate carcinogenesis. Functional inactivation of GSTP1 increases the …

Pharmacological effects and potential clinical usefulness of polyphenols in benign prostatic hyperplasia

K Mitsunari, Y Miyata, T Matsuo, Y Mukae, A Otsubo… - Molecules, 2021 - mdpi.com
Benign prostatic hyperplasia (BPH) is arguably the most common benign disease among
men. This disease is often associated with lower urinary tract symptoms (LUTS) in men and …