Recent progress in pneumococcal protein vaccines

S Li, H Liang, SH Zhao, XY Yang, Z Guo - Frontiers in Immunology, 2023 - frontiersin.org
Pneumococcal infections continue to pose a significant global health concern, necessitating
the development of effective vaccines. Despite the progress shown by pneumococcal …

Beyond the polysaccharide and glycoconjugate vaccines for Streptococcus pneumoniae: Does protein/peptide nanovaccines hold promises?

HH Chandpa, AK Panda, CL Meena, J Meena - Vaccine, 2023 - Elsevier
Streptococcus pneumoniae having almost 98 serotypes and being common cause of acute
otitis media, pneumonia, bacteremia, meningitis etc., which results in high mortality and …

[HTML][HTML] A bacterial vesicle-based pneumococcal vaccine against influenza-mediated secondary Streptococcus pneumoniae pulmonary infection

S Majumder, P Li, S Das, TN Nafiz, S Kumar, G Bai… - Mucosal …, 2024 - Elsevier
Streptococcus pneumoniae (Spn) is a common pathogen causing a secondary bacterial
infection following influenza, which leads to severe morbidity and mortality during seasonal …

[HTML][HTML] Liposome-based dry powder vaccine immunization targeting the lungs induces broad protection against pneumococcus

TC Rodrigues, DB Figueiredo, VM Gonçalves… - Journal of Controlled …, 2024 - Elsevier
Streptococcus pneumoniae is an important human pathogen. Currently used conjugate
vaccines are effective against invasive disease, but protection is restricted to serotypes …

Intranasal B5 promotes mucosal defence against Actinobacillus pleuropneumoniae via ameliorating early immunosuppression

J Huang, W Kang, D Yi, S Zhu, Y Xiang, C Liu, H Li… - Virulence, 2024 - Taylor & Francis
Actinobacillus pleuropneumoniae (APP) is an important pathogen of the porcine respiratory
disease complex, which leads to huge economic losses worldwide. We previously …

Novel method for production and purification of untagged pneumococcal surface protein A from clade 1

T da Costa Rodrigues, P Zorzete, EN Miyaji… - Applied Microbiology …, 2024 - Springer
Streptococcus pneumoniae can cause diseases with high mortality and morbidity. The
licensed vaccines are based on capsular polysaccharides and induce antibodies with low …

Evolution of Vaccines Formulation to Tackle the Challenge of Anti-Microbial Resistant Pathogens

F Tognetti, M Biagini, M Denis, F Berti… - International Journal of …, 2023 - mdpi.com
The increasing diffusion of antimicrobial resistance (AMR) across more and more bacterial
species emphasizes the urgency of identifying innovative treatment strategies to counter its …