Transcriptional differences enable the generation of alternative phenotypes from the same
genome. In malaria parasites, transcriptional plasticity plays a major role in the process of …

The erythrocyte invasion phase plays a critical role in multiplication, sexual determination,
and drug resistance in Plasmodium falciparum. In order to identify the critical genes and …

Malaria is a global health burden, and a major cause of mortality and morbidity in Africa.
Here we designed a putative malaria epitope ensemble vaccine by selecting an optimal set …

Various factors have been associated with the ongoing high prevalence of malaria in
Ghana. Among these are poor sanitation, low socioeconomic status (SES), building …

Invasion of human erythrocytes is essential for Plasmodium falciparum parasite survival and
pathogenesis, and is also a complex phenotype. While some later steps in invasion appear …

The central role that erythrocyte invasion plays in Plasmodium falciparum survival and
reproduction makes this process an attractive target for therapeutic or vaccine development …

Ex vivo phenotyping of P. falciparum erythrocyte invasion diversity is important in the
identification and down selection of potential malaria vaccine targets. However, due to the …

Human erythrocytes are indispensable for Plasmodium falciparum development. Unlike
other eukaryotic cells, there is no existing erythroid cell line capable of supporting long-term …

Introducción. La malaria por Plasmodium falciparum es una enfermedad causante de altas
tasas de morbimortalidad a nivel mundial. Diferentes candidatos a vacuna se han evaluado …

Malaria, a disease caused by Plasmodium parasites, is widespread throughout tropical and
sub-tropical regions worldwide; it mostly affects children and pregnant woman. Eradication …