Background Malignant transformation of hepatocellular adenomas (HCAs) into
hepatocellular carcinomas (HCCs) has been reported repeatedly and is considered to be …

The major risk factors and etiological agents responsible for development of hepatocellular
carcinoma in humans have been identified and characterized. Among these are chronic …

Hepatocellular carcinoma (HCC) is a slowly developing malignancy postulated to evolve
from premalignant lesions in chronically damaged livers. However, it was never established …

The early stages of hepatocarcinogenesis in human chronic liver diseases are characterized
by the emergence of preneoplastic lesions of which some will eventually develop into …

The Eastern woodchuck (Marmota monax) harbors a DNA virus (Woodchuck hepatitis virus
[WHV]) that is similar in structure and replicative life cycle to the human hepatitis B virus …

Background/Aims: In previous studies we found strong evidence for the existence and
activation in human liver of putative progenitor cells resembling oval cells in rat liver. In view …

Precancerous lesions that may be detected in chronically diseased, usually cirrhotic livers,
include: clusters of hepatocytes with atypia and increased proliferative rate (dysplastic foci) …

Hepatocellular carcinoma (HCC) accounts for 8–90% of liver cancers and is one of the most
frequent carcinomas throughout the world. The disease is more prevalent in parts of Africa …

Primary liver carcinomas in children and young adults are uncommon and poorly described.
We examined primary liver carcinomas in people younger than 30 years and performed …

Predictive value of liver cell dysplasia for development of hepatocellular carcinoma in
patients with non‐cirrhotic and cirrhotic chronic viral hepatitis Aims: Hepatocellular …