Monoclonal antibodies against rabies: current uses in prophylaxis and in therapy

GD de Melo, J Hellert, R Gupta, D Corti… - Current opinion in …, 2022 - Elsevier
Highlights•mAbs are suitable to replace rabies immunoglobulins in rabies prophylaxis.•mAb
cocktails are recommended to limit the risk of failure due limited coverage and viral …

Immunotherapies against human bacterial and fungal infectious diseases: A review

H Qadri, AH Shah, M Alkhanani, A Almilaibary… - Frontiers in …, 2023 - frontiersin.org
Nations' ongoing struggles with a number of novel and reemerging infectious diseases,
including the ongoing global health issue, the SARS-Co-V2 (severe acute respiratory …

Extremely potent human monoclonal antibodies from COVID-19 convalescent patients

E Andreano, E Nicastri, I Paciello, P Pileri… - Cell, 2021 - cell.com
Human monoclonal antibodies are safe, preventive, and therapeutic tools that can be rapidly
developed to help restore the massive health and economic disruption caused by the …

Safety, tolerability, and Plasmodium falciparum transmission-reducing activity of monoclonal antibody TB31F: a single-centre, open-label, first-in-human, dose …

SC van der Boor, MJ Smit, SW van Beek… - The Lancet Infectious …, 2022 - thelancet.com
Background Malaria elimination requires interruption of the highly efficient transmission of
Plasmodium parasites by mosquitoes. TB31F is a humanised monoclonal antibody that …

Heterotypic interactions drive antibody synergy against a malaria vaccine candidate

RJ Ragotte, D Pulido, AM Lias, D Quinkert… - Nature …, 2022 - nature.com
Understanding mechanisms of antibody synergy is important for vaccine design and
antibody cocktail development. Examples of synergy between antibodies are well …

Recent advances in immunotherapies against infectious diseases

D Ramamurthy, T Nundalall, S Cingo… - Immunotherapy …, 2021 - academic.oup.com
Immunotherapies are disease management strategies that target or manipulate components
of the immune system. Infectious diseases pose a significant threat to human health as …

Monoclonal antibodies block transmission of genetically diverse Plasmodium falciparum strains to mosquitoes

RM de Jong, L Meerstein-Kessel, DF Da, S Nsango… - NPJ vaccines, 2021 - nature.com
Malaria parasite transmission to mosquitoes relies on the uptake of sexual stage parasites
during a blood meal and subsequent formation of oocysts on the mosquito midgut wall …

BCG vaccine: a hope to control COVID-19 pandemic amid crisis

YS Malik, MI Ansari, B Ganesh, S Sircar… - Human Vaccines & …, 2020 - Taylor & Francis
ABSTRACT COVID-19 caused by the virus SARS-CoV-2 has gripped essentially all
countries in the world, and has infected millions and killed hundreds of thousands of people …

Monoclonal antibody applications in travel medicine

HK de Jong, MP Grobusch - Tropical Diseases, Travel Medicine and …, 2024 - Springer
For decades, immunoglobulin preparations have been used to prevent or treat infectious
diseases. Since only a few years, monoclonal antibody applications (mAbs) are taking flight …

Subcutaneous delivery of an antibody against SARS-CoV-2 from a supramolecular hydrogel depot

CM Kasse, CY Anthony, AE Powell, GA Roth… - Biomaterials …, 2023 - pubs.rsc.org
Prolonged maintenance of therapeutically-relevant levels of broadly neutralizing antibodies
(bnAbs) is necessary to enable passive immunization against infectious disease …