Vector microbiota manipulation by host antibodies: the forgotten strategy to develop transmission-blocking vaccines

A Maitre, A Wu-Chuang, J Aželytė, V Palinauskas… - Parasites & vectors, 2022 - Springer
Human and animal pathogens that are transmitted by arthropods are a global concern,
particularly those vectored by ticks (eg Borrelia burgdorferi and tick-borne encephalitis virus) …

Vaccinomics: A future avenue for vaccine development against emerging pathogens

J de la Fuente, M Contreras - Expert Review of Vaccines, 2021 - Taylor & Francis
Introduction Vaccines are a major achievement in medical sciences, but the development of
more effective vaccines against infectious diseases is essential for prevention and control of …

Tick saliva and its role in pathogen transmission

PA Nuttall - Wiener klinische Wochenschrift, 2019 - Springer
Tick saliva is a complex mixture of peptidic and non-peptidic molecules that aid
engorgement. The composition of tick saliva changes as feeding progresses and the tick …

[HTML][HTML] Innovative approaches for the control of ticks and tick-borne diseases

J de la Fuente, L Mazuecos, M Contreras - Ticks and Tick-Borne Diseases, 2023 - Elsevier
Ticks and tick-borne diseases constitute a major threat for human and animal health
worldwide. Vaccines for the control of tick infestations and transmitted pathogens still …

Oral vaccine formulation combining tick Subolesin with heat inactivated mycobacteria provides control of cross-species cattle tick infestations

PD Kasaija, M Contreras, F Kabi, S Mugerwa… - Vaccine, 2022 - Elsevier
Tick vaccines are necessary as part of a One Health approach for the control of tick
infestations and tick-borne diseases. Subolesin (SUB, also known as 4D8) is a tick …

Bombyx mori Akirin hijacks a viral peptide vSP27 encoded by BmCPV circRNA and activates the ROS-NF-κB pathway against viral infection

Y Zhang, X Zhang, K Dai, M Zhu, Z Liang, J Pan… - International Journal of …, 2022 - Elsevier
Bombyx mori cypovirus (BmCPV), a member of the family Reoviridae, is a model of
Cypovirus, has a 10 segmented double-stranded RNA genome. However, so far, only one …

Vaccination with Recombinant Subolesin Antigens Provides Cross-Tick Species Protection in Bos indicus and Crossbred Cattle in Uganda

PD Kasaija, M Contreras, F Kabi, S Mugerwa, J Fuente - Vaccines, 2020 - mdpi.com
Cattle tick infestations and transmitted pathogens affect animal health, production and
welfare with an impact on cattle industry in tropical and subtropical countries. Anti-tick …

Why new vaccines for the control of ectoparasite vectors have not been registered and commercialized?

J de la Fuente, A Estrada-Peña - Vaccines, 2019 - mdpi.com
The prevention and control of vector-borne diseases is a priority for improving global health.
Despite recent advances in the characterization of ectoparasite-host-pathogen molecular …

A novel combined scientific and artistic approach for the advanced characterization of interactomes: the Akirin/Subolesin model

S Artigas-Jerónimo, JJ Pastor Comín, M Villar… - Vaccines, 2020 - mdpi.com
The main objective of this study was to propose a novel methodology to approach
challenges in molecular biology. Akirin/Subolesin (AKR/SUB) are vaccine protective …

The correlation between subolesin-reactive epitopes and vaccine efficacy

M Contreras, PD Kasaija, F Kabi, S Mugerwa… - Vaccines, 2022 - mdpi.com
Vaccination is an environmentally-friendly alternative for tick control. The tick antigen
Subolesin (SUB) has shown protection in vaccines for the control of multiple tick species in …