[HTML][HTML] Overlapping mechanisms of action of brain-active bacteria and bacterial metabolites in the pathogenesis of common brain diseases

TP Eicher, MH Mohajeri - Nutrients, 2022 - mdpi.com
The involvement of the gut microbiota and the metabolites of colon-residing bacteria in brain
disease pathogenesis has been covered in a growing number of studies, but comparative …

[HTML][HTML] Ribosome biogenesis in disease: new players and therapeutic targets

L Jiao, Y Liu, XY Yu, X Pan, Y Zhang, J Tu… - … and Targeted Therapy, 2023 - nature.com
The ribosome is a multi-unit complex that translates mRNA into protein. Ribosome
biogenesis is the process that generates ribosomes and plays an essential role in cell …

[HTML][HTML] Dl-3-n-butylphthalide rescues dopaminergic neurons in Parkinson's disease models by inhibiting the NLRP3 inflammasome and ameliorating mitochondrial …

R Que, J Zheng, Z Chang, W Zhang, H Li, Z Xie… - Frontiers in …, 2021 - frontiersin.org
Background Neuroinflammation and mitochondrial impairment play important roles in the
neuropathogenesis of Parkinson's disease (PD). The activation of NLRP3 inflammasome …

Role of enteric glia and microbiota-gut-brain axis in parkinson disease pathogenesis

JCC Dos Santos, MPP Lima, GA de Castro Brito… - Ageing research …, 2023 - Elsevier
The microbiota-gut-brain axis or simple gut-brain axis (GBA) is a complex and interactive
bidirectional communication network linking the gut to the brain. Alterations in the …

[HTML][HTML] Efficacy of repetitive transcranial magnetic stimulation in Parkinson's disease: a systematic review and meta-analysis of randomised controlled trials

W Zhang, B Deng, F Xie, H Zhou, JF Guo, H Jiang… - …, 2022 - thelancet.com
Background Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive form of
brain stimulation that positively regulates the motor and non-motor symptoms of Parkinson's …

The conceivable role of prolactin hormone in Parkinson disease: The same goal but with different ways

HM Al-Kuraishy, MS Jabir, AI Al-Gareeb… - Ageing Research …, 2023 - Elsevier
Parkinson disease (PD) is a progressive neurodegenerative disease (NDD) of the brain. It
has been reported that prolactin (PRL) hormone plays a differential effect in PD, may be …

[HTML][HTML] Immunological mechanisms of inflammatory diseases caused by gut microbiota dysbiosis: A review

J Chu, S Feng, C Guo, B Xue, K He, L Li - Biomedicine & …, 2023 - Elsevier
The gut microbiota is indispensable for maintaining host health by enhancing the host's
digestive capacity, safeguarding the intestinal epithelial barrier, and preventing pathogen …

[HTML][HTML] Dysbiosis of Gut Microbiota from the Perspective of the Gut–Brain Axis: Role in the Provocation of Neurological Disorders

M Kandpal, O Indari, B Baral, S Jakhmola, D Tiwari… - Metabolites, 2022 - mdpi.com
The gut–brain axis is a bidirectional communication network connecting the gastrointestinal
tract and central nervous system. The axis keeps track of gastrointestinal activities and …

[HTML][HTML] Neuroprotective Effects of Bifidobacterium breve CCFM1067 in MPTP-Induced Mouse Models of Parkinson's Disease

T Li, C Chu, L Yu, Q Zhai, S Wang, J Zhao, H Zhang… - Nutrients, 2022 - mdpi.com
There is mounting evidence that the microbiota–gut–brain axis (MGBA) is critical in the
pathogenesis and progression of Parkinson's disease (PD), suggesting that probiotic …

[HTML][HTML] Fecal microbiota transplantation in Parkinson's disease—A randomized repeat-dose, placebo-controlled clinical pilot study

HL DuPont, J Suescun, ZD Jiang, EL Brown… - Frontiers in …, 2023 - frontiersin.org
Background and purpose The intestinal microbiome plays a primary role in the
pathogenesis of neurodegenerative disorders and may provide an opportunity for disease …