[HTML][HTML] Leveraging diverse cell-death patterns to predict the prognosis and drug sensitivity of triple-negative breast cancer patients after surgery

Y Zou, J Xie, S Zheng, W Liu, Y Tang, W Tian… - International Journal of …, 2022 - Elsevier
Background Postoperative progression and chemotherapy resistance is the major cause of
treatment failure in patients with triple-negative breast cancer (TNBC). Currently, there is a …

Disulfidptosis classification of hepatocellular carcinoma reveals correlation with clinical prognosis and immune profile

T Wang, K Guo, D Zhang, H Wang, J Yin, H Cui… - International …, 2023 - Elsevier
A new mode of cell death, disulfidptosis, has been discovered. Clinical prognostic
significance of disulfidptosis related pattern in hepatocellular carcinoma (HCC). In this study …

The pan-cancer multi-omics landscape of FOXO family relevant to clinical outcome and drug resistance

J Xie, J Zhang, W Tian, Y Zou, Y Tang, S Zheng… - International Journal of …, 2022 - mdpi.com
The forkhead box O (FOXO) transcription factors (TFs) family are frequently mutated,
deleted, or amplified in various human cancers, making them attractive candidates for …

Disulfidptosis-associated LncRNAs index predicts prognosis and chemotherapy drugs sensitivity in cervical cancer

L Liu, J Liu, Q Lyu, J Huang, Y Chen, C Feng, Y Liu… - Scientific reports, 2023 - nature.com
Disulfidptosis is a newly discovered form of cell death. Not yet clearly classified as
programmed cell death or accidental cell death. This study aimed to create a novel …

Based on disulfidptosis, revealing the prognostic and immunological characteristics of renal cell carcinoma with tumor thrombus of vena cava and identifying potential …

L Yang, J Liu, S Li, X Liu, F Zheng, S Xu, B Fu… - Journal of cancer …, 2023 - Springer
Background Patients with clear cell renal cell carcinoma (ccRCC) with venous tumor
thrombus have a poor prognosis, high surgical risk, and lack of targeted therapeutic agents …

Integrated multi-omics identified the novel intratumor microbiome-derived subtypes and signature to predict the outcome, tumor microenvironment heterogeneity, and …

B Zhang, J Liu, H Li, B Huang, B Zhang… - Frontiers in …, 2023 - frontiersin.org
Background: The extremely malignant tumour known as pancreatic cancer (PC) lacks
efficient prognostic markers and treatment strategies. The microbiome is crucial to how …

Construction and validation of a novel pyroptosis-related four-lncRNA prognostic signature related to gastric cancer and immune infiltration

Z Wang, L Cao, S Zhou, J Lyu, Y Gao… - Frontiers in …, 2022 - frontiersin.org
Increasing evidence has demonstrated that pyroptosis, a type of inflammatory programmed
cell death, plays an important role in the pathogenesis and progression of gastric cancer …

Exploration and validation of key genes associated with early lymph node metastasis in thyroid carcinoma using weighted gene co-expression network analysis and …

Y Liu, Z Yin, Y Wang, H Chen - Frontiers in Endocrinology, 2023 - frontiersin.org
Background Thyroid carcinoma (THCA), the most common endocrine neoplasm, typically
exhibits an indolent behavior. However, in some instances, lymph node metastasis (LNM) …

Genomic hallmarks and therapeutic targets of ribosome biogenesis in cancer

Y Zang, X Ran, J Yuan, H Wu, Y Wang… - Briefings in …, 2024 - academic.oup.com
Hyperactive ribosome biogenesis (RiboSis) fuels unrestricted cell proliferation, whereas
genomic hallmarks and therapeutic targets of RiboSis in cancers remain elusive, and …

Identification and targeting of cancer-associated fibroblast signature genes for prognosis and therapy in Cutaneous melanoma

G Zhang, P Ji, P Xia, H Song, Z Guo, X Hu… - Computers in Biology …, 2023 - Elsevier
Abstract Background Cancer-associated fibroblasts (CAFs) play pivotal roles in tumor
invasion and metastasis. However, studies on CAF biomarkers in Cutaneous Melanoma …