Advancements in the pharmaceutical applications of probiotics: Dosage forms and formulation technology

KC Baral, R Bajracharya, SH Lee… - International journal of …, 2021 - Taylor & Francis
Probiotics have demonstrated their high potential to treat and/or prevent various diseases
including neurodegenerative disorders, cancers, cardiovascular diseases, and inflammatory …

Using the intranasal route to administer drugs to treat neurological and psychiatric illnesses: rationale, successes, and future needs

A Lofts, F Abu-Hijleh, N Rigg, RK Mishra, T Hoare - CNS drugs, 2022 - Springer
While the intranasal administration of drugs to the brain has been gaining both research
attention and regulatory success over the past several years, key fundamental and …

Cannabidiol for the treatment of brain disorders: therapeutic potential and routes of administration

GTY Yau, W Tai, JC Arnold, HK Chan… - Pharmaceutical …, 2023 - Springer
The use of cannabidiol (CBD) for treating brain disorders has gained increasing interest.
While the mechanism of action of CBD in these conditions is still under investigation, CBD …

Nose-to-brain delivery of therapeutic peptides as nasal aerosols

W Alabsi, BB Eedara, D Encinas-Basurto, R Polt… - Pharmaceutics, 2022 - mdpi.com
Central nervous system (CNS) disorders, such as psychiatric disorders, neurodegeneration,
chronic pain, stroke, brain tumor, spinal cord injury, and many other CNS diseases, would …

In vitro studies on nasal formulations of nanostructured lipid carriers (NLC) and solid lipid nanoparticles (SLN)

CP Costa, S Barreiro, JN Moreira, R Silva, H Almeida… - Pharmaceuticals, 2021 - mdpi.com
The nasal route has been used for many years for the local treatment of nasal diseases.
More recently, this route has been gaining momentum, due to the possibility of targeting the …

Lipid and polymeric nanoparticles: successful strategies for nose-to-Brain drug delivery in the treatment of depression and anxiety disorders

M Alberto, AC Paiva-Santos, F Veiga, PC Pires - Pharmaceutics, 2022 - mdpi.com
Intranasal administration has gained an increasing interest for brain drug delivery since it
allows direct transport through neuronal pathways, which can be quite advantageous for …

Recent trends in praziquantel nanoformulations for helminthiasis treatment

AC Mengarda, B Iles, JP F. Longo… - Expert Opinion on Drug …, 2022 - Taylor & Francis
Introduction Infections caused by parasitic flatworms impose a considerable worldwide
health burden. Recently, World Health Organization launched its roadmap for neglected …

Recent advances in intranasal administration for brain-targeting delivery: a comprehensive review of lipid-based nanoparticles and stimuli-responsive gel formulations

J Koo, C Lim, KT Oh - International Journal of Nanomedicine, 2024 - Taylor & Francis
Addressing disorders related to the central nervous system (CNS) remains a complex
challenge because of the presence of the blood-brain barrier (BBB), which restricts the entry …

Advanced particulate carrier-mediated technologies for nasal drug delivery

VP Chavda, G Jogi, N Shah, MN Athalye… - Journal of Drug Delivery …, 2022 - Elsevier
Nasal drug delivery has been employed as an alternate and convenient route for the
systemic availability of pharmaceuticals, particularly for potent therapeutics. This is owing to …

Advances and future perspectives of intranasal drug delivery: A scientometric review

D Xu, XJ Song, X Chen, JW Wang, YL Cui - Journal of Controlled Release, 2024 - Elsevier
Intranasal drug delivery is as a noninvasive and efficient approach extensively utilized for
treating the local, central nervous system, and systemic diseases. Despite numerous …