[HTML][HTML] NLRP3 inflammasome involves in the pathophysiology of sepsis-induced myocardial dysfunction by multiple mechanisms

H Zhang, J Liao, L Jin, Y Lin - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Sepsis-induced myocardial dysfunction (SIMD) is one of the serious health-affecting
problems worldwide. At present, the mechanisms of SIMD are still not clearly elucidated. The …

Phytochemical characterization of Typha domingensis and the assessment of therapeutic potential using in vitro and in vivo biological activities and in silico studies

R Dilshad, KR Khan, S Ahmad… - Frontiers in …, 2023 - frontiersin.org
Typha domingensis, a medicinal plant with significant traditional importance for curing
various human diseases, has potentially bioactive compounds but was less explored …

From seeds to survival rates: investigating Linum usitatissimum's potential against ovarian cancer through network pharmacology

MM Islam, N Sreeharsha, FM Alshabrmi… - Frontiers in …, 2023 - frontiersin.org
Ovarian cancer is a malignant tumor that primarily forms in the ovaries. It often goes
undetected until it has spread to the pelvis and abdomen, making it more challenging to treat …

Novel Drug Discovery: Advancing Alzheimer's Therapy through Machine Learning and Network Pharmacology

FM Alshabrmi, FFA Alkhayl, A Rehman - European Journal of …, 2024 - Elsevier
Abstract Alzheimer's disease (AD), marked by tau tangles and amyloid-beta plaques, leads
to cognitive decline. Despite extensive research, its complex etiology remains elusive …

Two new constituents from the endophyte of Alternaria alternata and its anti-neuroinflammatory activity guided by molecular docking

X Yang, L Chen, G Wan, J Liu, B Zhao… - Natural Product …, 2023 - Taylor & Francis
Abstract Two new compounds, 3-hydroxy-1-(3-hydroxy-5-methoxyphenyl)-2-methyl propan-
1-one (1) and 1, 2, 6-trihydroxy-8-methoxy-2, 3, 3a, 9b-tetrahydrocyclopenta [c] isochromen …