Broad receptor engagement of an emerging global coronavirus may potentiate its diverse cross-species transmissibility

W Li, RJG Hulswit, SP Kenney… - Proceedings of the …, 2018 - National Acad Sciences
Porcine deltacoronavirus (PDCoV), identified in 2012, is a common enteropathogen of
swine with worldwide distribution. The source and evolutionary history of this virus is …

Diabetes and COVID-19; a bidirectional interplay

P Kazakou, V Lambadiari, I Ikonomidis… - Frontiers in …, 2022 - frontiersin.org
There seems to be a bidirectional interplay between Diabetes mellitus (DM) and coronavirus
disease 2019 (COVID-19). On the one hand, people with diabetes are at higher risk of fatal …

A mouse model for MERS coronavirus-induced acute respiratory distress syndrome

AS Cockrell, BL Yount, T Scobey, K Jensen… - Nature …, 2016 - nature.com
Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel virus that emerged in
2012, causing acute respiratory distress syndrome (ARDS), severe pneumonia-like …

Differential plasmacytoid dendritic cell phenotype and type I Interferon response in asymptomatic and severe COVID-19 infection

M Severa, RA Diotti, MP Etna, F Rizzo, S Fiore… - PLoS …, 2021 - journals.plos.org
SARS-CoV-2 fine-tunes the interferon (IFN)-induced antiviral responses, which play a key
role in preventing coronavirus disease 2019 (COVID-19) progression. Indeed, critically ill …

Animal models for SARS and MERS coronaviruses

LM Gretebeck, K Subbarao - Current opinion in virology, 2015 - Elsevier
Highlights•Animal coronaviruses can cause severe respiratory illness and death in
humans.•Coronavirus vaccines and antiviral drugs are not yet available.•Animal models are …

Generation of a transgenic mouse model of Middle East respiratory syndrome coronavirus infection and disease

AS Agrawal, T Garron, X Tao, BH Peng… - Journal of …, 2015 - Am Soc Microbiol
ABSTRACT The emergence of Middle East respiratory syndrome-coronavirus (MERS-CoV)
in the Middle East since 2012 has caused more than 900 human infections with∼ 40 …

Host species restriction of Middle East respiratory syndrome coronavirus through its receptor, dipeptidyl peptidase 4

N van Doremalen, KL Miazgowicz… - Journal of …, 2014 - Am Soc Microbiol
Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012. Recently, the
MERS-CoV receptor dipeptidyl peptidase 4 (DPP4) was identified and the specific …

Animal models, zoonotic reservoirs, and cross-species transmission of emerging human-infecting coronaviruses

Y Kane, G Wong, GF Gao - Annual review of animal biosciences, 2023 - annualreviews.org
Over the past three decades, coronavirus (CoV) diseases have impacted humans more than
any other emerging infectious disease. The recent emergence of severe acute respiratory …

Mouse-adapted MERS coronavirus causes lethal lung disease in human DPP4 knockin mice

K Li, CL Wohlford-Lenane… - Proceedings of the …, 2017 - National Acad Sciences
The Middle East respiratory syndrome (MERS) emerged in Saudi Arabia in 2012, caused by
a zoonotically transmitted coronavirus (CoV). Over 1,900 cases have been reported to date …

MERS: emergence of a novel human coronavirus

VS Raj, ADME Osterhaus, RAM Fouchier… - Current opinion in …, 2014 - Elsevier
Highlights•In 2012 a novel coronavirus emerged in the Middle East region.•MERS-CoV
causes a severe lower respiratory tract infection in humans.•Dromedary camels were found …