The endoplasmic reticulum (ER) is the key organelle for membrane biogenesis. Most lipids
are synthesized in the ER, and most membrane proteins are first inserted into the ER …

The sheet‐like lipid bilayer is the fundamental structural component of all cell membranes.
Its building blocks are phospholipids and cholesterol. Their amphiphilic structure …

Biological membranes have a stunning ability to adapt their composition in response to
physiological stress and metabolic challenges. Little is known how such perturbations affect …

Membrane proteins play key roles in human health, contributing to cellular signaling, ATP
synthesis, immunity, and metabolite transport. Protein folding is the pivotal early step for their …

Listeria monocytogenes is a foodborne bacterial pathogen that causes listeriosis. Positive
regulatory factor A (PrfA) is a pleiotropic master activator of virulence genes of L …

Cell biology through the macroscopic lens | Nature Physics Skip to main content Thank you for
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Plasma membranes appear as deformable systems wherein molecules are free to move and
diffuse giving rise to condensed microdomains (composed of ordered lipids, transmembrane …

Delineating the interactions of cellular metabolites with lipid membranes and their effects on
membrane physical and mechanical properties constitutes a key step for comprehensively …

Life is hypothesized to have emerged in a heterogenous prebiotic soup that potentially
comprised a variety of chemical moieties. One relevant consideration in this scenario is that …

Cell organelles feature characteristic lipid compositions that lead to differences in
membrane properties. In living cells, membrane ordering and fluidity are commonly …