Signaling pathways in rheumatoid arthritis: implications for targeted therapy

Q Ding, W Hu, R Wang, Q Yang, M Zhu, M Li… - Signal transduction and …, 2023 - nature.com
Rheumatoid arthritis (RA) is an incurable systemic autoimmune disease. Disease
progression leads to joint deformity and associated loss of function, which significantly …

Update on the pathomechanism, diagnosis, and treatment options for rheumatoid arthritis

YJ Lin, M Anzaghe, S Schülke - Cells, 2020 - mdpi.com
Rheumatoid arthritis (RA) is an autoimmune disease that involves multiple joints bilaterally.
It is characterized by an inflammation of the tendon (tenosynovitis) resulting in both cartilage …

The association between systemic immune-inflammation index and rheumatoid arthritis: evidence from NHANES 1999–2018

B Liu, J Wang, Y Li, K Li, Q Zhang - Arthritis research & therapy, 2023 - Springer
Purpose We aimed to explore the relationship between the systemic immune-inflammation
index (SII) and rheumatoid arthritis (RA) using NHANES from 1999 to 2018. Methods We …

Small interfering RNAs in the management of human rheumatoid arthritis

G Gargano, F Oliva, A Oliviero… - British Medical Bulletin, 2022 - academic.oup.com
Background Rheumatoid arthritis (RA) has unclear pathogenesis, but the molecules that
feed its inflammatory state are known. Small interfering RNAs (siRNAs) are useful to identify …

Angiogenesis as a potential treatment strategy for rheumatoid arthritis

Y Wang, H Wu, R Deng - European journal of pharmacology, 2021 - Elsevier
Angiogenesis is an early and key event in the pathogenesis of rheumatoid arthritis (RA) and
is crucial for the proliferation of synovial tissue and the formation of pannus. This process is …

Curcumin and curcuma longa extract in the treatment of 10 types of autoimmune diseases: A systematic review and meta-analysis of 31 randomized controlled trials

L Zeng, T Yang, K Yang, G Yu, J Li, W Xiang… - Frontiers in …, 2022 - frontiersin.org
Objective To evaluate the randomized controlled trials (RCTs) of Curcumin and Curcuma
longa Extract in the treatment of autoimmune diseases. Methods Databases such as …

CAR-T regulatory (CAR-Treg) cells: engineering and applications

M Arjomandnejad, AL Kopec, AM Keeler - Biomedicines, 2022 - mdpi.com
Regulatory T cells are critical for maintaining immune tolerance. Recent studies have
confirmed their therapeutic suppressive potential to modulate immune responses in organ …

A brief overview: sex differences in prevalent chronic musculoskeletal conditions

DS Overstreet, LJ Strath, M Jordan, IA Jordan… - International journal of …, 2023 - mdpi.com
Musculoskeletal (MSK) pain disorders are some of the most prevalent and disabling chronic
pain conditions worldwide. These chronic conditions have a considerable impact on the …

Recent advances in nanoparticle-based drug delivery systems for rheumatoid arthritis treatment

S Nasra, D Bhatia, A Kumar - Nanoscale advances, 2022 - pubs.rsc.org
Nanotechnology has increasingly emerged as a promising tool for exploring new
approaches, from treating complex conditions to early detection of the onset of multiple …

Recent advances in nano-targeting drug delivery systems for rheumatoid arthritis treatment

H Li, R Gou, J Liao, Y Wang, R Qu, Q Tang… - Acta Materia …, 2023 - scienceopen.com
Rheumatoid arthritis is a systemic inflammatory disease that can lead to articular cartilage
destruction and periarticular bone erosion, thus ultimately compromising joint integrity and …