HLA-A alleles influencing NK cell function impact AML relapse following allogeneic hematopoietic cell transplantation
K van der Ploeg, JB Le Luduec, PA Stevenson… - Blood …, 2020 - ashpublications.org
HLA-B allotypes exhibiting the Bw4 epitope trigger variable inhibitory signaling of KIR3DL1
receptor types, where strong inhibitory HLA-B and KIR3DL1 allele combinations are …
receptor types, where strong inhibitory HLA-B and KIR3DL1 allele combinations are …
The role of the HLA class I α2 helix in determining ligand hierarchy for the killer cell ig-like receptor 3DL1
PM Saunders, BJ MacLachlan, J Widjaja… - The Journal of …, 2021 - journals.aai.org
HLA class I molecules that represent ligands for the inhibitory killer cell Ig-like receptor (KIR)
3DL1 found on NK cells are categorically defined as those HLA-A and HLA-B allotypes …
3DL1 found on NK cells are categorically defined as those HLA-A and HLA-B allotypes …
[HTML][HTML] High-Resolution Analysis Identifies High Frequency of KIR-A Haplotypes and Inhibitory Interactions of KIR With HLA Class I in Zhejiang Han
S Tao, Y He, KM Kichula, J Wang, J He… - Frontiers in …, 2021 - frontiersin.org
Killer cell immunoglobulin-like receptors (KIR) interact with human leukocyte antigen (HLA)
class I molecules, modulating critical NK cell functions in the maintenance of human health …
class I molecules, modulating critical NK cell functions in the maintenance of human health …
[HTML][HTML] Killer immunoglobulin-like receptor allele determination using next-generation sequencing technology
B Maniangou, N Legrand, M Alizadeh, U Guyet… - Frontiers in …, 2017 - frontiersin.org
The impact of natural killer (NK) cell alloreactivity on hematopoietic stem cell transplantation
(HSCT) outcome is still debated due to the complexity of graft parameters, HLA class I …
(HSCT) outcome is still debated due to the complexity of graft parameters, HLA class I …
[HTML][HTML] Conservation, extensive heterozygosity, and convergence of signaling potential all indicate a critical role for KIR3DL3 in higher primates
Natural killer (NK) cell functions are modulated by polymorphic killer cell immunoglobulin-
like receptors (KIR). Among 13 human KIR genes, which vary by presence and copy …
like receptors (KIR). Among 13 human KIR genes, which vary by presence and copy …
[HTML][HTML] KIR variation in Iranians combines high haplotype and allotype diversity with an abundance of functional inhibitory receptors
Natural killer (NK) cells are innate lymphocytes that eliminate infected and transformed cells.
They discriminate healthy from diseased tissue through killer cell Ig-like receptor (KIR) …
They discriminate healthy from diseased tissue through killer cell Ig-like receptor (KIR) …
[HTML][HTML] Multiplex interrogation of the NK cell signalome reveals global downregulation of CD16 signaling during lentivirus infection through an IL-18/ADAM17 …
S Sugawara, B Hueber, G Woolley, K Terry… - PLoS …, 2023 - journals.plos.org
Despite their importance, natural killer (NK) cell responses are frequently dysfunctional
during human immunodeficiency virus-1 (HIV-1) and simian immunodeficiency virus (SIV) …
during human immunodeficiency virus-1 (HIV-1) and simian immunodeficiency virus (SIV) …
Association of KIR genes and MHC class I ligands with atopic dermatitis
Atopic dermatitis (AD) is a chronic illness that is associated with immune dysregulation. NK
cell function has previously been associated with AD. NK cells directly interact with …
cell function has previously been associated with AD. NK cells directly interact with …
[HTML][HTML] KIR3DL1/S1 allotypes contribute differentially to the development of Behçet disease
H Petrushkin, PJ Norman, E Lougee… - The Journal of …, 2019 - journals.aai.org
Behçet disease is a chronic, relapsing-remitting autoinflammatory syndrome with a strong
HLA-B* 51 association. In this paper, we describe a human cohort of 267 individuals with …
HLA-B* 51 association. In this paper, we describe a human cohort of 267 individuals with …
[HTML][HTML] Fluctuating and geographically specific selection characterize rapid evolution of the human KIR region
The killer-cell immunoglobulin-like receptor (KIR) region comprises a fast-evolving family of
genes that encode receptors for natural killer (NK) cells and have crucial role in host …
genes that encode receptors for natural killer (NK) cells and have crucial role in host …