Background: Middle East respiratory syndrome (MERS) is a lower respiratory tract disease
caused by a beta coronavirus (CoV) called MERS-CoV, characterized by a high mortality …

Allogeneic hematopoietic cell transplantation (HCT) is the most established form of cancer
immunotherapy and has been successfully applied for the treatment and cure of otherwise …

Natural killer cells (NK) have been associated with the pathophysiology of atopic dermatitis
(AD). NK function is regulated by killer cell Ig-like receptor family (KIR) receptors that interact …

Immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors (IRs) enable
discrimination between self-and non-self molecules on the surface of host target cells. In this …

Cytotoxic T lymphocyte (CTL) and natural killer (NK) cell responses to a single optimal 10-
mer epitope (KK10) in the human immunodeficiency virus type-1 (HIV-1) protein p24Gag are …

Tyrosine kinase inhibitor (TKI)–treated chronic myeloid leukemia (CML) patients with
increased NK cell number have a better prognosis, and thus, NK cells may suppress CML …

The development of BCR-ABL1 tyrosine kinase inhibitors (TKIs) markedly improved the
prognosis of patients with chronic myeloid leukemia (CML). Approximately 50% of patients …

Allelic diversity of the KIR2DL receptors drive differential expression and ligand-binding
affinities that impact natural killer cell function and patient outcomes for diverse cancers. We …

Although the prognosis of chronic myeloid leukemia (CML) in blastic crisis remains poor,
some patients achieve long-term remission after allogeneic hematopoietic stem cell …

The majority of established KIR clinical assessment algorithms used for donor selection for
hematopoietic progenitor cell transplantation (HPCT) evaluate gene content …