Electron microscopy studies of soft nanomaterials
This review highlights recent efforts on applying electron microscopy (EM) to soft (including
biological) nanomaterials. We will show how developments of both the hardware and …
biological) nanomaterials. We will show how developments of both the hardware and …
3D electron diffraction for chemical analysis: Instrumentation developments and innovative applications
T Gruene, E Mugnaioli - Chemical Reviews, 2021 - ACS Publications
In the past few years, many exciting papers reported results based on crystal structure
determination by electron diffraction. The aim of this review is to provide general and …
determination by electron diffraction. The aim of this review is to provide general and …
MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography
MyD88 and MAL are Toll-like receptor (TLR) adaptors that signal to induce pro-inflammatory
cytokine production. We previously observed that the TIR domain of MAL (MALTIR) forms …
cytokine production. We previously observed that the TIR domain of MAL (MALTIR) forms …
Serial protein crystallography in an electron microscope
Serial X-ray crystallography at free-electron lasers allows to solve biomolecular structures
from sub-micron-sized crystals. However, beam time at these facilities is scarce, and …
from sub-micron-sized crystals. However, beam time at these facilities is scarce, and …
Ab initio phasing macromolecular structures using electron-counted MicroED data
Structures of two globular proteins were determined ab initio using microcrystal electron
diffraction (MicroED) data that were collected on a direct electron detector in counting mode …
diffraction (MicroED) data that were collected on a direct electron detector in counting mode …
Benchmarking the ideal sample thickness in cryo-EM
MW Martynowycz, MTB Clabbers… - Proceedings of the …, 2021 - National Acad Sciences
The relationship between sample thickness and quality of data obtained is investigated by
microcrystal electron diffraction (MicroED). Several electron microscopy (EM) grids …
microcrystal electron diffraction (MicroED). Several electron microscopy (EM) grids …
An expandable hydrogen-bonded organic framework characterized by three-dimensional electron diffraction
A molecular crystal of a 2-D hydrogen-bonded organic framework (HOF) undergoes an
unusual structural transformation after solvent removal from the crystal pores during …
unusual structural transformation after solvent removal from the crystal pores during …
Microenvironment of pancreatic inflammation: calling for nanotechnology for diagnosis and treatment
L Liu, Y Zhang, X Li, J Deng - Journal of Nanobiotechnology, 2023 - Springer
Acute pancreatitis (AP) is a common and life-threatening digestive disorder. However, its
diagnosis and treatment are still impeded by our limited understanding of its etiology …
diagnosis and treatment are still impeded by our limited understanding of its etiology …
Electron diffraction of 3D molecular crystals
Electron crystallography has a storied history which rivals that of its more established X-ray-
enabled counterpart. Recent advances in data collection and analysis have sparked a …
enabled counterpart. Recent advances in data collection and analysis have sparked a …
Better, faster, cheaper: recent advances in cryo–electron microscopy
Cryo–electron microscopy (cryo-EM) continues its remarkable growth as a method for
visualizing biological objects, which has been driven by advances across the entire pipeline …
visualizing biological objects, which has been driven by advances across the entire pipeline …