Systemic lupus erythematosus (SLE) is an autoimmune and multisystem disease with a high
public health impact. Lupus nephritis (LN), commonly known as renal involvement in SLE, is …

Background: The familial clustering phenomenon together with environmental influences
indicates the presence of a genetic and epigenetic predisposition to systematic lupus …

Abstract Ubiquitin-specific peptidases7 (USP7) participates in the regulation of various
metabolic and immune disorders. However, the role of USP7 in lupus nephritis (LN) remains …

Background The interplay between gut microbiome genera and inflammatory kidney-related
diseases, such as nephrotic syndrome, glomerulonephritis, tubulo-interstitial nephritis, and …

Background Lupus nephritis (LN) is the most common and serious complication of systemic
lupus erythematosus (SLE). LN pathogenesis is not fully understood. Axl receptor tyrosine …

Background Lupus nephritis (LN) is the most common complication of systemic lupus
erythematosus (SLE). The limited treatment options for LN increase the economic burdens …

We previously reported that co-delivery of dihydroartemisinin and high mobility group box 1
(HMGB1) siRNAs, using cell penetrating peptide (TAT)-modified cationic liposomes (TAT …

KH-type splicing regulatory protein (KSRP) is an RNA-binding protein that promotes mRNA
decay and thereby negatively regulates cytokine expression at the post-transcriptional level …

Neutrophils are important immune cells act as the body's first line of defense against
infection and respond to diverse inflammatory cues. Many studies have demonstrated that …

Background This study aimed to access whether serum human epididymis protein 4 (HE4)
level could identify lupus nephritis (LN) pathological classes in adults and children. Methods …