Beyond their role as a cellular powerhouse, mitochondria are emerging as integral players
in molecular signaling and cell fate determination through reactive oxygen species (ROS) …

In this paper, the author enumerates cardiac defects with a functionally single ventricle,
summarizes single ventricle physiology, presents a summary of management strategies to …

Abstract Aims The Fontan operation has resulted in improved survival in patients with single‐
ventricle congenital heart disease. As a result, there is a growing population of teenagers …

In patients with a functionally univentricular heart, the Fontan strategy achieves separation of
the systemic and pulmonary circulation and reduction of ventricular volume overload …

The Fontan procedure has provided patients with single ventricle physiology extended
survival into adulthood and in many cases has improved their quality of life. Atrioventricular …

Because of remarkable surgical and medical advances over the past several decades, there
are growing numbers of infants and children living with single ventricle congenital heart …

Individuals with Fontan circulation are at risk of late mortality from both cardiac and
noncardiac causes. Despite the known risk of mortality, referral indications for advanced …

Aims The incidence of hepatocellular carcinoma (HCC) in patients with Fontan-associated
liver disease (ie, FALD-HCC) has increased over time. However, the risk factors for HCC …

Background As more patients survive into adulthood with repaired congenital heart disease
(CHD), transplant centers now have patients presenting with both end-stage cardiac and …

Fontan associated liver disease is associated with morbidity and mortality in palliated single-
ventricle congenital heart disease patients. Magnetic resonance elastography (MRE) …