Diagnosis and treatment of primary aldosteronism

M Reincke, I Bancos, P Mulatero, UI Scholl… - The lancet Diabetes & …, 2021 - thelancet.com
Primary aldosteronism is a common cause of secondary hypertension associated with
excess cardiovascular morbidities. Primary aldosteronism is underdiagnosed because it …

Primary aldosteronism—a multidimensional syndrome

AF Turcu, J Yang, A Vaidya - Nature Reviews Endocrinology, 2022 - nature.com
Primary aldosteronism is a common cause of hypertension and is a risk factor for
cardiovascular and renal morbidity and mortality, via mechanisms mediated by both …

Japan Endocrine Society clinical practice guideline for the diagnosis and management of primary aldosteronism 2021

M Naruse, T Katabami, H Shibata, M Sone… - Endocrine …, 2022 - jstage.jst.go.jp
Primary aldosteronism (PA) is associated with higher cardiovascular morbidity and mortality
rates than essential hypertension. The Japan Endocrine Society (JES) has developed an …

Testing for primary aldosteronism and mineralocorticoid receptor antagonist use among US veterans: a retrospective cohort study

JB Cohen, DL Cohen, DS Herman… - Annals of internal …, 2021 - acpjournals.org
Background: Primary aldosteronism is a common cause of treatment-resistant hypertension.
However, evidence from local health systems suggests low rates of testing for primary …

The expanding spectrum of primary aldosteronism: implications for diagnosis, pathogenesis, and treatment

A Vaidya, P Mulatero, R Baudrand… - Endocrine …, 2018 - academic.oup.com
Primary aldosteronism is characterized by aldosterone secretion that is independent of renin
and angiotensin II and sodium status. The deleterious effects of primary aldosteronism are …

Primary aldosteronism: state-of-the-art review

A Vaidya, GL Hundemer, K Nanba… - American Journal of …, 2022 - academic.oup.com
We are witnessing a revolution in our understanding of primary aldosteronism (PA). In the
past 2 decades, we have learned that PA is a highly prevalent syndrome that is largely …

Pathogenesis and treatment of primary aldosteronism

MC Zennaro, S Boulkroun… - Nature Reviews …, 2020 - nature.com
Early diagnosis and appropriate treatment of primary aldosteronism, the most frequent
cause of secondary hypertension, are crucial to prevent deleterious cardiovascular …

Evolution of the primary aldosteronism syndrome: updating the approach

A Vaidya, RM Carey - The Journal of Clinical Endocrinology & …, 2020 - academic.oup.com
Context New approaches are needed to address the evolution of the primary aldosteronism
syndrome and to increase its recognition. Herein, we review evidence indicating that primary …

Primary aldosteronism in patients in China with recently detected hypertension

Z Xu, J Yang, J Hu, Y Song, W He, T Luo… - Journal of the American …, 2020 - jacc.org
Abstract Background A total of 44.7% adults in China have hypertension, but the prevalence
of primary aldosteronism (PA) in Chinese hypertensive patients is unknown. Objectives This …

[HTML][HTML] [11C]metomidate PET-CT versus adrenal vein sampling for diagnosing surgically curable primary aldosteronism: a prospective, within-patient trial

X Wu, R Senanayake, E Goodchild, WA Bashari… - Nature Medicine, 2023 - nature.com
Primary aldosteronism (PA) due to a unilateral aldosterone-producing adenoma is a
common cause of hypertension. This can be cured, or greatly improved, by adrenal surgery …