Abstract The N6-methyladenosine (m6A) modification is regulated by methylases, commonly
referred to as “writers,” and demethylases, known as “erasers,” leading to a dynamic and …

Epigenetic modifications have received increasing attention and have been shown to be
extensively involved in kidney development and disease progression. Among them, the …

Abstract Background N4-acetylcytidine (ac4C) as a significant RNA modification has been
reported to maintain the stability of mRNA and to regulate the translation process. However …

Septic acute kidney injury (AKI) is characterized by inflammation. Pyroptosis often occurs
during AKI and is associated with the development of septic AKI. This study found that …

Aims To investigate the role and mechanisms of methyltransferase-like 3 (METTL3) in the
pathogenesis of lipopolysaccharide (LPS)-induced acute lung injury (ALI). Main methods …

Multiple mechanisms are involved in kidney damage, among which the role of epigenetic
modifications in the occurrence and development of kidney diseases is constantly being …

Sepsis is defined as life‐threatening organ dysfunction caused by the host immune
dysregulation to infection. It is a highly heterogeneous syndrome with complex …

Although great efforts have been made to elucidate the pathological mechanisms of renal
diseases and potential prevention and treatment targets that would allow us to retard kidney …

Abstract RNA N 6-methyladenosine (m 6 A) methylation is the most abundant and
conserved RNA modification in eukaryotes. It participates in the regulation of RNA …

Background: Numerous studies have suggested that long non-coding RNA (lncRNA) affects
the progression of ischemic acute kidney injury (IAKI). However, little information is currently …