Techniques for navigating postsurgical adhesions: Insights into mechanisms and future directions

J Chen, X Tang, Z Wang, A Perez, B Yao… - Bioengineering & …, 2023 - Wiley Online Library
Postsurgical adhesions are a common complication of surgical procedures that can lead to
postoperative pain, bowel obstruction, infertility, as well as complications with future …

Research progress of quercetin in cardiovascular disease

W Zhang, Y Zheng, F Yan, M Dong… - Frontiers in Cardiovascular …, 2023 - frontiersin.org
Quercetin is one of the most common flavonoids. More and more studies have found that
quercetin has great potential utilization value in cardiovascular diseases (CVD), such as …

Cellular and molecular pathways of COVID-19 and potential points of therapeutic intervention

JP Hussman - Frontiers in pharmacology, 2020 - frontiersin.org
With the objective of linking early findings relating to the novel SARS-CoV-2 coronavirus
with potentially informative findings from prior research literature and to promote …

MMP-2 and its implications on cardiac function and structure: interplay with inflammation in hypertension

TR Vitorino, AF do Prado, SB de Assis Cau… - Biochemical …, 2023 - Elsevier
Hypertension is one of the leading risk factors for the development of heart failure. Despite
being a multifactorial disease, in recent years, preclinical and clinical studies suggest strong …

[HTML][HTML] CD11b mediates hypertensive cardiac remodeling by regulating macrophage infiltration and polarization

YL Zhang, J Bai, WJ Yu, QY Lin, HH Li - Journal of Advanced Research, 2024 - Elsevier
Introduction Leukocyte infiltration is an early event during cardiac remodeling frequently
leading to heart failure (HF). Integrins mediate leukocyte infiltration during inflammation …

Blocking VCAM-1 prevents angiotensin II-induced hypertension and vascular remodeling in mice

L Yin, J Bai, WJ Yu, Y Liu, HH Li, QY Lin - Frontiers in pharmacology, 2022 - frontiersin.org
Adhesion of monocytes to the vascular endothelium frequently leads to an inflammatory
response, which contributes to hypertension and vascular remodeling. Vascular cellular …

Integrin CD11b contributes to hypertension and vascular dysfunction through mediating macrophage adhesion and migration

QY Lin, J Bai, YL Zhang, HH Li - Hypertension, 2023 - Am Heart Assoc
Background: Leukocyte adhesion to endothelium is an early inflammatory response and is
mainly controlled by the β2-integrins. However, the role of integrin CD11b/CD18 in the …

[HTML][HTML] Quercetin dihydrate inhibition of cardiac fibrosis induced by angiotensin II in vivo and in vitro

L Wang, A Tan, X An, Y Xia, Y Xie - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Cardiac fibroblasts play a key role in the process of myocardial remodeling and myocardial
fibrosis, which will eventually lead to heart failure. Quercetin Dihydrate has been studied in …

Key player in cardiac hypertrophy, emphasizing the role of toll-like receptor 4

Z Xiao, B Kong, H Yang, C Dai, J Fang, T Qin… - Frontiers in …, 2020 - frontiersin.org
Toll-like receptor 4 (TLR4), a key pattern recognition receptor, initiates the innate immune
response and leads to chronic and acute inflammation. In the past decades, accumulating …

[HTML][HTML] Resolvin-D1 attenuation of angiotensin II-induced cardiac inflammation in mice is associated with prevention of cardiac remodeling and hypertension

F Olivares-Silva, N De Gregorio… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Aims Despite the broad pharmacological arsenal to treat hypertension, chronic patients may
develop irreversible cardiac remodeling and fibrosis. Angiotensin II, the main peptide …