Counteracting immunosuppression in the tumor microenvironment by oncolytic Newcastle disease virus and cellular immunotherapy

V Schirrmacher, S van Gool, W Stuecker - International Journal of …, 2022 - mdpi.com
An apparent paradox exists between the evidence for spontaneous systemic T cell-mediated
anti-tumor immune responses in cancer patients, observed particularly in their bone marrow …

Oncolytic myxoma virus is effective in murine models of triple negative breast cancer despite poor rates of infection

RJ Thomas, MY Bartee, M Valenzuela-Cardenas… - Molecular Therapy …, 2023 - cell.com
Oncolytic viruses are being heavily investigated as novel methods to treat cancers; however,
predicting their therapeutic efficacy remains challenging. The most commonly used …

Innovative retargeted oncolytic herpesvirus against nectin4-positive cancers

A Vannini, F Parenti, C Forghieri, C Barboni… - Frontiers in Molecular …, 2023 - frontiersin.org
Nectin4 is a recently discovered tumor associated antigen expressed in cancers that
constitute relevant unmet clinical needs, including the undruggable triple negative breast …

TheraVision: Engineering platform technology for the development of oncolytic viruses based on herpes simplex virus type 1

C Funk, N Uhlig, Z Ruzsics, F Baur, M Peindl… - Molecular Therapy …, 2024 - cell.com
Viruses are able to efficiently penetrate cells, multiply, and eventually kill infected cells,
release tumor antigens, and activate the immune system. Therefore, viruses are highly …

Current perspectives on Vaxinia virus: an immuno-oncolytic vector in cancer therapy

SD Kaur, AD Singh, DN Kapoor - Medical Oncology, 2023 - Springer
Viruses are being researched as cutting-edge therapeutic agents in cancer due to their
selective oncolytic action against malignancies. Immuno-oncolytic viruses are a potential …

Oncolytic virus therapy for cancer treatment

M Llobet Casajuana - 2023 - diposit.ub.edu
In the last few years, oncolytic virus therapy has been increasingly recognised as a new
class of immunotherapy for the treatment of cancer. To date, a variety of oncolytic viruses …

[PDF][PDF] Research News. Publications, 2020. Volume 4

S Majumdar - 2020 - egrove.olemiss.edu
23. Eissa IH, Ibrahim MK, Metwaly AM, Belal A, Mehany ABM, Abdelhady AA, Elhendawy
MA, Radwan MM, ElSohly MA, Mahdy HA. Design, molecular docking, in vitro, and in vivo …