Several studies have shown that bone morphogenetic proteins (BMPs) can influence
adipogenic and osteogenic cell lineages. We have shown that a peptide derived from BMP …

Biomaterials that can control the behaviour of stem cells play a major role in regenerative
medicine and tissue engineering. We previously showed that poly (epsilon) caprolactone …

As the populations of the Western world become older, they will suffer more and more from
bone defects related to osteoporosis (non-union fractures, vertebral damages), cancers …

A critical‐size bone defect cannot repair itself. These defects are presently filled by bone
grafts or with biomaterials that mimic bone properties. The activity of bone cells is modulated …

Bone defects that cannot “heal spontaneously during life” will become an ever greater health
problem as populations age. Harvesting autografts has several drawbacks, such as pain …

In the well-known superfamily of transforming growth factors beta (TGF-b), bone
morphogenetic proteins (BMPs) are one of the most compelling cytokines for their major role …

This chapter reviews biochemical and other interactions of cells with bioactive glasses and
related ceramics. An extensive amount of research work has been carried out to improve the …

In the last three decades, tissue engineering has emerged as a new discipline with the aim
of addressing serious clinical cases where the spontaneous repair of damaged tissue is …

Delayed fracture healing is a major health issue involved with aging. Therefore, strategies to
improve the pace of repair and prevent non-union are needed in order to improve patient …