P2Y12 inhibitor monotherapy in patients undergoing percutaneous coronary intervention

D Capodanno, U Baber, DL Bhatt, JP Collet… - Nature Reviews …, 2022 - nature.com
For 20 years, dual antiplatelet therapy (DAPT), consisting of the combination of aspirin and a
platelet P2Y12 receptor inhibitor, has been the gold standard of antithrombotic …

Short duration of DAPT versus de-escalation after percutaneous coronary intervention for acute coronary syndromes

C Laudani, A Greco, G Occhipinti, S Ingala… - Cardiovascular …, 2022 - jacc.org
Objectives The aim of this study was to compare short dual antiplatelet therapy (DAPT) and
de-escalation in a network meta-analysis using standard DAPT as common comparator …

Oral antiplatelet therapy after acute coronary syndrome: a review

H Kamran, H Jneid, WT Kayani, SS Virani, GN Levine… - Jama, 2021 - jamanetwork.com
Importance Acute coronary syndrome (ACS) is a major cause of morbidity and mortality in
the United States with an annual incidence of approximately 1 million. Dual antiplatelet …

The impact of the stress hyperglycemia ratio on short-term and long-term poor prognosis in patients with acute coronary syndrome: insight from a large cohort study in …

J Yang, Y Zheng, C Li, J Gao, X Meng, K Zhang… - Diabetes …, 2022 - Am Diabetes Assoc
OBJECTIVE In recent years, some studies have indicated that a novel marker described as
the stress hyperglycemia ratio (SHR) can reflect true acute hyperglycemic status and is …

High-sensitivity cardiac troponin on presentation to rule out myocardial infarction: a stepped-wedge cluster randomized controlled trial

A Anand, KK Lee, AR Chapman, AV Ferry… - Circulation, 2021 - Am Heart Assoc
Background: High-sensitivity cardiac troponin assays enable myocardial infarction to be
ruled out earlier, but the safety and efficacy of this approach is uncertain. We investigated …

First in-human results of computed tomography angiography for coronary stent assessment with a spectral photon counting computed tomography

S Boccalini, SA Si-Mohamed, H Lacombe… - Investigative …, 2022 - journals.lww.com
Objectives The aim of this study is to compare the image quality of in vivo coronary stents
between an energy integrating detectors dual-layer computed tomography (EID-DLCT) and …

Stroke–heart syndrome: recent advances and challenges

JF Scheitz, LA Sposato, J Schulz‐Menger… - Journal of the …, 2022 - Am Heart Assoc
After ischemic stroke, there is a significant burden of cardiovascular complications, both in
the acute and chronic phase. Severe adverse cardiac events occur in 10% to 20% of …

Clinical characteristics and prognosis of patients with microvascular angina: an international and prospective cohort study by the Coronary Vasomotor Disorders …

H Shimokawa, A Suda, J Takahashi… - European heart …, 2021 - academic.oup.com
Aims To provide multi-national, multi-ethnic data on the clinical characteristics and
prognosis of patients with microvascular angina (MVA). Methods and results The Coronary …

Effect of CYP2C19 Genotype on Ischemic Outcomes During Oral P2Y12 Inhibitor Therapy: A Meta-Analysis

NL Pereira, C Rihal, R Lennon, G Marcus… - Cardiovascular …, 2021 - jacc.org
Objectives The aim of this study was to examine the effect of CYP2C19 genotype on clinical
outcomes in patients with coronary artery disease (CAD) who predominantly underwent …

Dual antiplatelet therapy duration after percutaneous coronary intervention in high bleeding risk: a meta-analysis of randomized trials

F Costa, C Montalto, M Branca, SJ Hong… - European Heart …, 2023 - academic.oup.com
Aims The optimal duration of dual antiplatelet therapy (DAPT) after percutaneous coronary
intervention (PCI) in patients at high bleeding risk (HBR) is still debated. The current study …