[HTML][HTML] Insights into N6-methyladenosine and programmed cell death in cancer
L Liu, H Li, D Hu, Y Wang, W Shao, J Zhong, S Yang… - Molecular Cancer, 2022 - Springer
Abstract N6-methyladenosine (m6A) methylation, the most common form of internal RNA
modification in eukaryotes, has gained increasing attention and become a hot research topic …
modification in eukaryotes, has gained increasing attention and become a hot research topic …
[HTML][HTML] FOXM1 and cancer: faulty cellular signaling derails homeostasis
Forkhead box transcription factor, FOXM1 is implicated in several cellular processes such as
proliferation, cell cycle progression, cell differentiation, DNA damage repair, tissue …
proliferation, cell cycle progression, cell differentiation, DNA damage repair, tissue …
[HTML][HTML] Demethylase ALKBH5 suppresses invasion of gastric cancer via PKMYT1 m6A modification
Y Hu, C Gong, Z Li, J Liu, Y Chen, Y Huang, Q Luo… - Molecular cancer, 2022 - Springer
Background Gastric cancer (GC) is one of the most pernicious tumors that seriously harm
human healthcare. GC metastasis is one of the prime cause of failed cancer treatment, but …
human healthcare. GC metastasis is one of the prime cause of failed cancer treatment, but …
[HTML][HTML] Pan-cancer analysis shows that ALKBH5 is a potential prognostic and immunotherapeutic biomarker for multiple cancer types including gliomas
C Wei, B Wang, D Peng, X Zhang, Z Li, L Luo… - Frontiers in …, 2022 - frontiersin.org
Background AlkB homolog 5 (ALKBH5) is a N6-methyladenosine (m6A) demethylase
associated with the development, growth, and progression of multiple cancer types …
associated with the development, growth, and progression of multiple cancer types …
[HTML][HTML] Warburg effect-promoted exosomal circ_0072083 releasing up-regulates NANGO expression through multiple pathways and enhances temozolomide …
C Ding, X Yi, X Chen, Z Wu, H You, X Chen… - Journal of Experimental …, 2021 - Springer
Background Temozolomide (TMZ) resistance limits its application in glioma. Exosome can
carry circular RNAs (circRNAs) to regulate drug resistance via sponging microRNAs …
carry circular RNAs (circRNAs) to regulate drug resistance via sponging microRNAs …
[HTML][HTML] ALKBH5 promotes lung fibroblast activation and silica-induced pulmonary fibrosis through miR-320a-3p and FOXM1
W Sun, Y Li, D Ma, Y Liu, Q Xu, D Cheng, G Li… - Cellular & molecular …, 2022 - Springer
Abstract Background N 6-methyladenosine (m6A) is the most common and abundant
internal modification of RNA. Its critical functions in multiple physiological and pathological …
internal modification of RNA. Its critical functions in multiple physiological and pathological …
[HTML][HTML] Potential therapeutic strategies for skeletal muscle atrophy
L Huang, M Li, C Deng, J Qiu, K Wang, M Chang… - Antioxidants, 2022 - mdpi.com
The maintenance of muscle homeostasis is vital for life and health. Skeletal muscle atrophy
not only seriously reduces people's quality of life and increases morbidity and mortality, but …
not only seriously reduces people's quality of life and increases morbidity and mortality, but …
[HTML][HTML] Potential roles of N6-methyladenosine (m6A) in immune cells
C Liu, Z Yang, R Li, Y Wu, M Chi, S Gao, X Sun… - Journal of Translational …, 2021 - Springer
Abstract N6-methyl-adenosine (m6A) is one of the most common internal modifications on
RNA molecules present in mammalian cells. Deregulation of m6A modification has been …
RNA molecules present in mammalian cells. Deregulation of m6A modification has been …
Curcumin prevents obesity by targeting TRAF4‐induced ubiquitylation in m6A‐dependent manner
Y Chen, R Wu, W Chen, Y Liu, X Liao, B Zeng… - EMBO …, 2021 - embopress.org
Obesity has become a major health problem that has rapidly prevailed over the past several
decades worldwide. Curcumin, a natural polyphenolic compound present in turmeric, has …
decades worldwide. Curcumin, a natural polyphenolic compound present in turmeric, has …
[HTML][HTML] N6-methyladenosine demethylase FTO promotes growth and metastasis of gastric cancer via m6A modification of caveolin-1 and metabolic regulation of …
Gastric cancer (GC) is the fifth most common tumor and the third most deadly cancer
worldwide. N6-methyladenosine (m6A) modification has been reported to play a regulatory …
worldwide. N6-methyladenosine (m6A) modification has been reported to play a regulatory …