Comparative efficacy of topical oclacitinib 0.1% and tacrolimus 0.01% in canine keratoconjunctivitis sicca

JK de Oliveira, DL Williams, C Bollmann… - Veterinary …, 2019 - Wiley Online Library
Objective To assess the efficacy of 0.1% oclacitinib as a single agent, and in combination
with tacrolimus 0.01%, for the control of ophthalmic signs of keratoconjunctivitis sicca (KCS) …

[HTML][HTML] Conjoint research of WGCNA, single-cell transcriptome and structural biology reveals the potential targets of IDD development and treatment and JAK3 …

Y Zhao, Y Mu, Y Zou, Z He, T Lu, X Wang, W Li… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Objectives: This study conducted integrated analysis of bulk RNA sequencing, single-cell
RNA sequencing and Weighted Gene Co-expression Network Analysis (WGCNA), to …

Novel therapies for alopecia areata: the era of rational drug development

ECE Wang, Z Dai, AM Christiano - Journal of Allergy and Clinical …, 2018 - Elsevier
Treatments for alopecia areata (AA) have evolved over the decades from broad and
nonspecific therapies to those that are now more targeted and rationally selected. This was …

Treatment of Discoid Lupus Erythematosus with Upadacitinib: A Case Report

W Hu, S Zhang, C Lian - Clinical, Cosmetic and Investigational …, 2023 - Taylor & Francis
Cutaneous lupus erythematosus (CLE) is a group of diseases within the spectrum of lupus
that primarily manifests with skin lesions. Discoid lupus erythematosus (DLE) is the most …

Evaluation of tolerability and efficacy of a topical emulgel containing nanoliposomal ruxolitinib phosphate in the treatment of mild atopic dermatitis: A before-after …

A Naeimifar, S Ahmad Nasrollahi… - Journal of …, 2022 - Taylor & Francis
Background Ruxolitinib is a JAK1/2 inhibitor, which inhibits the signal transduction of
interferon-gamma, a cytokine implicated in the pathogenesis of atopic dermatitis (AD). In this …

[HTML][HTML] Janus kinase inhibitors for the treatment of psoriatic arthritis

S Raychaudhuri, RJ Shah, SK Raychaudhuri… - Indian Journal of …, 2024 - ijdvl.com
Psoriatic arthritis (PsA), a systemic disease, has multi-domain musculoskeletal pathologies
along with dermatological manifestations. The current recommendations and the standard of …

[HTML][HTML] Epigenetic Methylation Changes in Pregnant Women: Bisphenol Exposure and Atopic Dermatitis

SH Kim, SY Yu, JH Choo, J Kim, K Ahn… - International Journal of …, 2024 - mdpi.com
Bisphenol is a chemical substance widely used in plastic products and food containers. In
this study, we observed a relationship between DNA methylation and atopic dermatitis (AD) …

Pyoderma Gangrenosum: what do we know now?

F McKenzie, M Arthur, AG Ortega-Loayza - Current Dermatology Reports, 2018 - Springer
Abstract Purpose of Review To summarize the recent literature on the pathophysiology,
diagnosis, and treatment of pyoderma gangrenosum. Recent Findings A complex interplay …

S100A8 (rs3806232) gene polymorphism and S100A8 serum level in psoriasis vulgaris patients: A preliminary study

A Farag, M Shoaib, A Labeeb, A Sleem… - Journal of Cosmetic …, 2022 - Wiley Online Library
Background S100A8 single nucleotide polymorphism (SNP) and S100A8 blood level are
related to many inflammatory disorders with no available conclusion in psoriasis. Aim The …

Good efficacy achieved by baricitinib in the treatment of anti-MDA5 antibody-positive dermatomyositis with alopecia areata

D Chen, W Huang, W Zhongjie, R Feifeng, L Luo… - …, 2022 - academic.oup.com
The patient, a 25-year-old female, was admitted to our hospital for evaluation of a 'rash, joint
pain in both hands, and muscular soreness in both upper limbs for 1month'. The physical …